ACG clinical guideline: genetic testing and management of hereditary gastrointestinal cancer syndromes

S Syngal, RE Brand, JM Church… - Official journal of the …, 2015 - journals.lww.com
This guideline presents recommendations for the management of patients with hereditary
gastrointestinal cancer syndromes. The initial assessment is the collection of a family history …

Hereditary colorectal cancer

HT Lynch, A De la Chapelle - New England Journal of Medicine, 2003 - Mass Medical Soc
Colorectal cancers among patients with a familial risk of this disorder account for
approximately one of five cases of this disease. Many cases can be prevented by the …

Pancreatic adenocarcinoma, version 2.2021, NCCN clinical practice guidelines in oncology

MA Tempero, MP Malafa, M Al-Hawary… - Journal of the National …, 2021 - jnccn.org
Pancreatic cancer is the fourth leading cause of cancer-related death among men and
women in the United States. A major challenge in treatment remains patients' advanced …

[BOOK][B] WHO classification of tumours of the digestive system.

FT Bosman, F Carneiro, RH Hruban, ND Theise - 2010 - cabidigitallibrary.org
This book is the third volume of the 4th Edition of the WHO series on histological and genetic
ty** of human tumours. It is an authoritative, concise reference book providing an …

Revised Bethesda Guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instability

A Umar, CR Boland, JP Terdiman… - Journal of the …, 2004 - academic.oup.com
Hereditary nonpolyposis colorectal cancer (HNPCC), also known as Lynch syndrome, is a
common autosomal dominant syndrome characterized by early age at onset, neoplastic …

New clinical criteria for hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome) proposed by the International Collaborative group on HNPCC

HFA Vasen, P Watson, JP Mecklin, HT Lynch - Gastroenterology, 1999 - Elsevier
New clinical criteria for hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome)
proposed by the International Collaborative Group on HNPCC - ScienceDirect Skip to main …

[HTML][HTML] Tumor microsatellite-instability status as a predictor of benefit from fluorouracil-based adjuvant chemotherapy for colon cancer

CM Ribic, DJ Sargent, MJ Moore… - … England Journal of …, 2003 - Mass Medical Soc
Background Colon cancers with high-frequency microsatellite instability have clinical and
pathological features that distinguish them from microsatellite-stable tumors. We …

Colorectal cancer screening and surveillance: clinical guidelines and rationale—update based on new evidence

S Winawer, R Fletcher, D Rex, J Bond, R Burt… - Gastroenterology, 2003 - Elsevier
We have updated guidelines for screening for colorectal cancer. The original guidelines
were prepared by a panel convened by the US Agency for Health Care Policy and Research …

The epigenetic progenitor origin of human cancer

AP Feinberg, R Ohlsson, S Henikoff - Nature reviews genetics, 2006 - nature.com
Cancer is widely perceived as a heterogeneous group of disorders with markedly different
biological properties, which are caused by a series of clonally selected genetic changes in …

DNA mismatch repair in cancer

M Baretti, DT Le - Pharmacology & therapeutics, 2018 - Elsevier
Microsatellite instability (MSI) refers to the hypermutator phenotype secondary to frequent
polymorphism in short repetitive DNA sequences and single nucleotide substitution, as …