The worse prognosis of right-sided compared with left-sided colon cancers: a systematic review and meta-analysis

M Yahagi, K Okabayashi, H Hasegawa… - Journal of …, 2016 - Elsevier
Background Right-sided colon cancers (RCC) and left-sided colon cancers (LCC) are of
different embryological origins, and various differences exist between them. However, the …

Genetic prognostic and predictive markers in colorectal cancer

A Walther, E Johnstone, C Swanton, R Midgley… - Nature Reviews …, 2009 - nature.com
Despite many studies of the likely survival outcome of individual patients with colorectal
cancer, our knowledge of this subject remains poor. Until recently, we had virtually no …

[HTML][HTML] ESMO Consensus Guidelines for management of patients with colon and rectal cancer. a personalized approach to clinical decision making

HJ Schmoll, E Van Cutsem, A Stein, V Valentini… - Annals of oncology, 2012 - Elsevier
Colorectal cancer (CRC) is the most common tumour type in both sexes combined in
Western countries. Although screening programmes including the implementation of faecal …

Pooled analysis of fluorouracil-based adjuvant therapy for stage II and III colon cancer: who benefits and by how much?

S Gill, CL Loprinzi, DJ Sargent, SD Thomé… - Journal of clinical …, 2004 - ascopubs.org
Purpose Although it is well-established that fluorouracil-(FU-) based adjuvant therapy
improves survival for patients with resected high-risk colon cancer, the magnitude of …

Colon cancer

R Labianca, GD Beretta, B Kildani, L Milesi… - Critical reviews in …, 2010 - Elsevier
Colon cancer is one of the leading tumours in the world and it is considered among the big
killers, together with lung, prostate and breast cancer. In the recent years very important …

[HTML][HTML] Clinical determinants of survival in patients with 5-fluorouracil-based treatment for metastatic colorectal cancer: results of a multivariate analysis of 3825 …

CH Köhne, D Cunningham, F Di Costanzo… - Annals of …, 2002 - Elsevier
Background Patients with metastatic colorectal cancer are usually offered systemic
chemotherapy as palliative treatment. A multivariate analysis was performed in order to …

Pathophysiology, clinical presentation, and management of colon cancer

MS Cappell - Gastroenterology Clinics of North America, 2008 - Elsevier
Colon cancer is believed to arise from two types of precursor polyps via two distinct
pathways: conventional adenomas by the conventional adenoma-to-carcinoma sequence …

Gene expression profiles and molecular markers to predict recurrence of Dukes' B colon cancer

Y Wang, T Jatkoe, Y Zhang, MG Mutch… - Journal of clinical …, 2004 - ascopubs.org
Purpose The 5-year survival rate of patients with Dukes' B colon cancer is approximately
75%. Identification of the patients at high risk of recurrence in this group would allow better …

Obstruction and perforation in colorectal adenocarcinoma: an analysis of prognosis and current trends

HS Chen, SM Sheen-Chen - Surgery, 2000 - Elsevier
Background: In adenocarcinoma of the colon and rectum, obstruction and perforation may
occur either alone or together at the site of the neoplasm or proximally. Both events carry a …

Initial presentation with stage IV colorectal cancer: how aggressive should we be?

SA Rosen, JF Buell, A Yoshida, S Kazsuba… - Archives of …, 2000 - jamanetwork.com
Hypothesis The appropriate surgical treatment of patients with colorectal cancer who are
found on initial presentation to have stage IV disease is controversial. With presumed limited …