Quantitative map** of deformation and elasticity in optical coherence tomography has
attracted much attention of researchers during the last two decades. However, despite …

Optical coherence tomography (OCT) is a non-contact method for imaging the topological
and internal microstructure of samples in three dimensions. OCT can be configured as a …

Inadequate margins in breast-conserving surgery (BCS) are associated with an increased
likelihood of local recurrence of breast cancer. Currently, approximately 20% of BCS …

Cancer cell invasion relies on an equilibrium between cell deformability and the biophysical
constraints imposed by the extracellular matrix (ECM). However, there is little consensus on …

The spiny mouse, Acomys cahirinus, is an adult mammal capable of remarkable feats of scar-
free tissue regeneration after damage to several organs including the skin and the heart …

Optical coherence elastography (OCE) is emerging as a method to image the mechanical
properties of tissue on the microscale. However, the spatial resolution, a main advantage of …

Background and objectives The mechanics of the nucleus depends on cellular structures
and architecture, and impact a number of diseases. Nuclear mechanics is yet rather complex …

Recent studies in mechanobiology have revealed the importance of cellular and
extracellular mechanical properties in regulating cellular function in normal and disease …

Many biological tissues have a complex hierarchical structure allowing them to function
under demanding physiological loading conditions. Structural changes caused by ageing or …

Compression optical coherence elastography (OCE) has shown promise in detecting
diseases, such as breast cancer, based on changes in the elasticity of tissue. While the …