Marine natural products

AR Carroll, BR Copp, RA Davis, RA Keyzers… - Natural product …, 2022 - pubs.rsc.org
Covering: 2020 This review covers the literature published in 2020 for marine natural
products (MNPs), with 757 citations (747 for the period January to December 2020) referring …

Heck macrocyclization in natural product total synthesis

W Zhang - Natural Product Reports, 2021 - pubs.rsc.org
Covering: 1981–2020 Heck macrocyclization is a logical extension of the award-winning
Mizoroki–Heck reaction. Through covalent linking of two otherwise discrete coupling …

Structural determination, total synthesis, and biological activity of iezoside, a highly potent Ca2+-ATPase inhibitor from the marine cyanobacterium Leptochromothrix …

N Kurisawa, A Iwasaki, K Teranuma… - Journal of the …, 2022 - ACS Publications
Sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) is a membrane protein on the
endoplasmic reticulum (ER) that transports Ca2+ from the cytosol into the ER. As its function …

Enantioselective Meerwein–Ponndorf–Verley reduction of β, γ-unsaturated α-keto esters by asymmetric binary-acid catalysis in the green solvent iPrOH

H Qiu, J Ren, L Zhang, R Song, W Si, D Yang… - Green …, 2023 - pubs.rsc.org
Enantioselective Meerwein–Ponndorf–Verley reduction of β, γ-unsaturated α-keto esters in
iPrOH alone was achieved by using asymmetric binary-acid catalysts. The presence of 0.2 …

Stereoselective synthesis of the northern hemisphere of the proposed structure of neaumycin B

H Sharma, S Paul, S Ganguly, SS Auddy… - Organic & …, 2024 - pubs.rsc.org
The stereoselective synthesis of the northern hemisphere (C20–C41) of the purported
structure of the extremely potent anticancer natural product neaumycin B has been …

Total synthesis of strasseriolide A

MH Sahana, D Saha, RK Goswami - The Journal of Organic …, 2022 - ACS Publications
Stereoselective total synthesis of structurally intriguing antimalarial macrolide strasseriolide
A has been accomplished by adopting a convergent approach. The salient features of this …

Site-directed late-stage diversification of macrocyclic nannocystins facilitating anticancer SAR and mode of action studies

H Zhang, Y Tian, X Yuan, F **e, S Yu, J Cai… - RSC Medicinal …, 2023 - pubs.rsc.org
Nannocystins are a family of 21-membered cyclodepsipeptides with excellent anticancer
activity. However, their macrocyclic architecture poses a significant challenge to structure …

Structure–Activity Relationship Study of Biselyngbyolide B Reveals Mitochondrial Fission-Induced Cytotoxicity in Cancer

P Mandal, D Paul, H Sharma, S Saha… - ACS Medicinal …, 2024 - ACS Publications
A systematic structure–activity relationship study of the potent anticancer marine macrolide
biselyngbyolide B has been accomplished. A total of 11 structural variants of the parent …

Sarco/Endoplasmic Reticulum Ca2+-ATPase (SERCA) Inhibitors Isolated from Subtropical Marine Cyanobacteria in Japan

A Iwasaki - New Tide of Natural Product Chemistry, 2023 - Springer
Marine cyanobacteria are prolific producers of natural products with novel structures and
potent biological activities. We have investigated the secondary metabolites of marine …

Bioactive Substances from Marine Cyanobacteria

K Suenaga, A Iwasaki - Marine Natural Products, 2020 - Springer
Marine cyanobacteria have been known as prolific producers of secondary metabolites that
have intriguing structures and remarkable biological activities. In fact, some of them have …