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Aptamer-based detection of circulating targets for precision medicine
L Wu, Y Wang, X Xu, Y Liu, B Lin, M Zhang… - Chemical …, 2021 - ACS Publications
The past decade has witnessed ongoing progress in precision medicine to improve human
health. As an emerging diagnostic technique, liquid biopsy can provide real-time …
health. As an emerging diagnostic technique, liquid biopsy can provide real-time …
Developmental origins of metabolic diseases
Almost 2 billion adults in the world are overweight, and more than half of them are classified
as obese, while nearly one-third of children globally experience poor growth and …
as obese, while nearly one-third of children globally experience poor growth and …
Biological functions and current advances in isolation and detection strategies for exosome nanovesicles
Abstract Exosomes are nanoscale (≈ 30–150 nm) extracellular vesicles of endocytic origin
that are shed by most types of cells and circulate in bodily fluids. Exosomes carry a specific …
that are shed by most types of cells and circulate in bodily fluids. Exosomes carry a specific …
Microfluidic‐based exosome analysis for liquid biopsy
B Lin, Y Lei, J Wang, L Zhu, Y Wu, H Zhang… - Small …, 2021 - Wiley Online Library
Liquid biopsy offers non‐invasive and real‐time molecular profiling of individual patients,
and is thus considered a revolutionary technology in precision medicine. Exosomes have …
and is thus considered a revolutionary technology in precision medicine. Exosomes have …
Early human trophoblast development: from morphology to function
M Gauster, G Moser, S Wernitznig, N Kupper… - Cellular and Molecular …, 2022 - Springer
Human pregnancy depends on the proper development of the embryo prior to implantation
and the implantation of the embryo into the uterine wall. During the pre-implantation phase …
and the implantation of the embryo into the uterine wall. During the pre-implantation phase …
Extracellular vesicles in obesity and diabetes mellitus
Cell-to-cell communication happens via diverse mechanisms including the synthesis,
release and transfer to target cells of extracellular vesicles (EVs). EVs include nanovesicles …
release and transfer to target cells of extracellular vesicles (EVs). EVs include nanovesicles …
Extracellular vesicle mediated embryo-endometrial cross talk during implantation and in pregnancy
Extracellular vesicles are lipoproteinaceous membrane-enclosed nanometer-sized
structures produced by cells and are thought to mediate cellular communications. Loaded …
structures produced by cells and are thought to mediate cellular communications. Loaded …
Human placental exosomes in gestational diabetes mellitus carry a specific set of miRNAs associated with skeletal muscle insulin sensitivity
There is increasing evidence that miRNAs, which are enriched in nanovesicles called
exosomes, are important regulators of gene expression. When compared with normal …
exosomes, are important regulators of gene expression. When compared with normal …
Regulation of maternal–fetal metabolic communication
CE Bowman, Z Arany, MJ Wolfgang - Cellular and molecular life sciences, 2021 - Springer
Pregnancy may be the most nutritionally sensitive stage in the life cycle, and improved
metabolic health during gestation and early postnatal life can reduce the risk of chronic …
metabolic health during gestation and early postnatal life can reduce the risk of chronic …
Placental exosomes profile in maternal and fetal circulation in intrauterine growth restriction-Liquid biopsies to monitoring fetal growth
Introduction Placenta-derived exosomes may represent an additional pathway by which the
placenta communicates with the maternal system to induce maternal vascular adaptations to …
placenta communicates with the maternal system to induce maternal vascular adaptations to …