Mutualism and pathogenesis in Xenorhabdus and Photorhabdus: two roads to the same destination

H Goodrich‐Blair, DJ Clarke - Molecular microbiology, 2007 - Wiley Online Library
Photorhabdus and Xenorhabdus bacteria colonize the intestines of the infective soil‐
dwelling stage of entomophagous nematodes, Heterorhabditis and Steinernema …

Photorhabdus and a Host of Hosts

NR Waterfield, T Ciche, D Clarke - Annual review of …, 2009 - annualreviews.org
Photorhabdus is a member of the family Enterobacteriaceae that lives in a mutualistic
association with a Heterorhabditis nematode worm. The nematode worm burrows into insect …

The genome sequence of the entomopathogenic bacterium Photorhabdus luminescens

E Duchaud, C Rusniok, L Frangeul, C Buchrieser… - Nature …, 2003 - nature.com
Photorhabdus luminescens is a symbiont of nematodes and a broad-spectrum insect
pathogen. The complete genome sequence of strain TT01 is 5,688,987 base pairs (bp) long …

Evolution-inspired engineering of nonribosomal peptide synthetases

KAJ Bozhüyük, L Präve, C Kegler, L Schenk, S Kaiser… - Science, 2024 - science.org
Many clinically used drugs are derived from or inspired by bacterial natural products that
often are produced through nonribosomal peptide synthetases (NRPSs), megasynthetases …

Photorhabdus: towards a functional genomic analysis of a symbiont and pathogen

R Ffrench-Constant, N Waterfield… - FEMS Microbiology …, 2003 - academic.oup.com
Pathogenicity and symbiosis are central to bacteria–host interactions. Although several
human pathogens have been subjected to functional genomic analysis, we still understand …

How the insect pathogen bacteria Bacillus thuringiensis and Xenorhabdus/Photorhabdus occupy their hosts

C Nielsen-LeRoux, S Gaudriault, N Ramarao… - Current opinion in …, 2012 - Elsevier
Insects are the largest group of animals on earth. Like mammals, virus, fungi, bacteria and
parasites infect them. Several tissue barriers and defense mechanisms are common for …

Bacterial symbionts and natural products

JM Crawford, J Clardy - Chemical communications, 2011 - pubs.rsc.org
The study of bacterial symbionts of eukaryotic hosts has become a powerful discovery
engine for chemistry. This highlight looks at four case studies that exemplify the range of …

A Single Promoter Inversion Switches Photorhabdus Between Pathogenic and Mutualistic States

VS Somvanshi, RE Sloup, JM Crawford, AR Martin… - Science, 2012 - science.org
Microbial populations stochastically generate variants with strikingly different properties,
such as virulence or avirulence and antibiotic tolerance or sensitivity. Photorhabdus …

Photorhabdus: a model for the analysis of pathogenicity and mutualism

DJ Clarke - Cellular microbiology, 2008 - Wiley Online Library
Photorhabdus are entomopathogenic members of the family Enterobacteriaceae. In addition
to killing insects Photorhabdus also have a mutualistic association with nematodes from the …

Photorhabdus heterorhabditis subsp. aluminescens subsp. nov., Photorhabdus heterorhabditis subsp. heterorhabditis subsp. nov., Photorhabdus australis subsp …

RAR Machado, A Muller, SM Ghazal… - … of Systematic and …, 2021 - microbiologyresearch.org
Three Gram-stain-negative, rod-shaped, non-spore-forming bacteria, BA1T, Q614T and
PB68. 1T, isolated from the digestive system of Heterorhabditis entomopathogenic …