To study complex biological processes holistically, it is imperative to take an integrative
approach that combines multi-omics data to highlight the interrelationships of the involved …

Ever present hurdles for the discovery of new drugs for cancer therapy have necessitated
the development of the alternative strategy of drug repurposing, the development of old …

Despite growing numbers of immune checkpoint blockade (ICB) trials with available omics
data, it remains challenging to evaluate the robustness of ICB response and immune …

Cancer treatment by immune checkpoint blockade (ICB) can bring long-lasting clinical
benefits, but only a fraction of patients respond to treatment. To predict ICB response, we …

The LinkedOmics database contains multi-omics data and clinical data for 32 cancer types
and a total of 11 158 patients from The Cancer Genome Atlas (TCGA) project. It is also the …

We are currently living in the “genomic era.” In the last decade, high-throughput genomic
analyses have generated massive quantities of data that can be used to explore gene …

Driven by the recent advances of next generation sequencing (NGS) technologies and an
urgent need to decode complex human diseases, a multitude of large-scale studies were …

Genetic variants have been associated with myriad molecular phenotypes that provide new
insight into the range of mechanisms underlying genetic traits and diseases. Identifying any …

Single-cell omics technologies are currently solving biological and medical problems that
earlier have remained elusive, such as discovery of new cell types, cellular differentiation …

Chinese ponies are endemic to the mountainous areas of southwestern China and were first
reported in the archaeological record at the Royal Tomb of Zhongshan King, Mancheng …