Present status of microfluidic PCR chip in nucleic acid detection and future perspective

S Chen, Y Sun, F Fan, S Chen, Y Zhang… - TrAC Trends in …, 2022 - Elsevier
Polymerase chain reaction (PCR) amplifies specific fragment of DNA molecules and has
been extensively applied in fields of pathogens and gene mutation detection, food safety …

Polymerase chain reaction in microfluidic devices

CD Ahrberg, A Manz, BG Chung - Lab on a Chip, 2016 - pubs.rsc.org
The invention of the polymerase chain reaction (PCR) has caused a revolution in molecular
biology, giving access to a method of amplifying deoxyribonucleic acid (DNA) molecules …

Point-of-care-testing of nucleic acids by microfluidics

L Zhang, B Ding, Q Chen, Q Feng, L Lin… - TrAC Trends in Analytical …, 2017 - Elsevier
Nucleic acid detection offers critical information in diagnosing pathogen infection and
monitoring disease treatment. Point-of-care testing (POCT), with ideal characteristics such …

Microfluidic electrochemical devices for pollution analysis–A review

J Kudr, O Zitka, M Klimanek, R Vrba, V Adam - Sensors and Actuators B …, 2017 - Elsevier
Pollution of environment represents serious issue, which deserves increased attention.
Conventional laboratory techniques, which rely on bench-top devices, do not satisfy …

Multiplex detection of bacteria on an integrated centrifugal disk using bead-beating lysis and loop-mediated amplification

H Yan, Y Zhu, Y Zhang, L Wang, J Chen, Y Lu, Y Xu… - Scientific Reports, 2017 - nature.com
Although culture-based identification of bacteria is the gold-standard for the diagnosis of
infectious diseases, it is time consuming. Recent advances in molecular diagnostics and …

Rapid detection of foodborne bacterial pathogens using visual high‐throughput microfluidic chip

Z **, G Ding, G Li, G Yang, Y Han… - Journal of Chemical …, 2020 - Wiley Online Library
BACKGROUND Foodborne diseases are a major global public health concern. It is urgent to
monitor foodborne pathogens from contaminated foods based on multi‐target detection …

Controlled-diffusion centrifugal microfluidic for rapid antibiotic susceptibility testing

Z Pang, S Li, S Wang, Z Cai, S Zhang, C Wan… - Analytica Chimica …, 2024 - Elsevier
The abuse of antibiotics has become a global public safety issue, leading to the
development of antimicrobial resistance (AMR). The development of antimicrobial …

A fully integrated nucleic acid analysis system for multiplex detection of genetic polymorphisms related to folic acid metabolism

B Lin, Z Geng, Y Chen, W Zeng, B Li, Y Zhang, P Liu - Lab on a Chip, 2023 - pubs.rsc.org
A sufficient intake of folic acid is essential during pregnancy, but several genetic
polymorphisms reduce its absorption, threaten the lives of pregnant women and cause …

[HTML][HTML] Evaluation of a micro/nanofluidic chip platform for the high-throughput detection of bacteria and their antibiotic resistance genes in post-neurosurgical …

G Zhang, G Zheng, Y Zhang, R Ma, X Kang - International Journal of …, 2018 - Elsevier
Background Post-neurosurgical meningitis (PNM) is one of the most severe hospital-
acquired infections worldwide, and a large number of pathogens, especially those …

SMART: A Swing-Assisted Multiplexed Analyzer for Point-of-Care Respiratory Tract Infection Testing

L Zhang, X Wang, D Liu, Y Wu, L Feng, C Han, J Liu… - Biosensors, 2023 - mdpi.com
Respiratory tract infections such as the ongoing coronavirus disease 2019 (COVID-19) has
seriously threatened public health in the last decades. The experience of fighting against the …