Pseudorabies virus (PRV) is a herpesvirus of swine, a member of the Alphaherpesvirinae
subfamily, and the etiological agent of Aujeszky's disease. This review describes the …

Herpesviruses replicate their DNA and package this DNA into capsids in the nucleus. These
capsids then face substantial obstacles to their release from cells. Unlike other DNA viruses …

The three-dimensional reconstruction of the bovine kidney pyruvate dehydrogenase
complex (M r≈ 7.8× 106) comprising about 22 molecules of pyruvate dehydrogenase (E1) …

Herpesvirus particles consist of four morphologically distinct structures, the core, capsid,
tegument, and envelope. The inner nucleoprotein core comprising the linear double …

Herpes simplex virus, a DNA virus of high complexity, consists of a nucleocapsid
surrounded by the tegument—a protein compartment—and the envelope. The latter …

Herpes simplex virus type I (HSV-1) is the causative agent of several pathologies ranging in
severity from the common cold sore to life-threatening encephalitic infection. During …

The life cycle of Kaposi's sarcoma-associated herpesvirus (KSHV) consists of two phases,
latent and lytic. The virus establishes latency as a strategy for avoiding host immune …

Genome replication and assembly of viruses often takes place in specific intracellular
compartments where viral components concentrate, thereby increasing the efficiency of the …

Alphaherpesviruses like herpes simplex virus are large DNA viruses characterized by their
ability to establish lifelong latent infection in neurons. As for all herpesviruses …

The order Herpesvirales contains viruses infecting animals from molluscs to men with a
common virion morphology which have been classified into the families Herpesviridae …