Going back to Kahlbaum's psychomotor (and GABAergic) origins: is catatonia more than just a motor and dopaminergic syndrome?

D Hirjak, KM Kubera, RC Wolf… - Schizophrenia …, 2020 - academic.oup.com
Abstract In 1874, Karl Kahlbaum described catatonia as an independent syndrome
characterized by motor, affective, and behavioral anomalies. In the following years, various …

Brain mechanisms underlying catatonia: A systematic review

G Cattarinussi, AA Gugliotta, D Hirjak, RC Wolf… - Schizophrenia …, 2024 - Elsevier
Background Catatonia is a complex psychomotor disorder characterized by motor, affective,
and behavioral symptoms. Despite being known for almost 150 years, its pathomechanisms …

Reactive psychoses in the context of the COVID-19 pandemic: clinical perspectives from a case series

MJ Valdés-Florido, Á López-Díaz… - Revista de psiquiatria y …, 2020 - Elsevier
Introduction The world is currently undergoing an extremely stressful scenario due to the
COVID-19 pandemic. This unexpected and dramatic situation could increase the incidence …

Lorazepam in catatonia–Past, present and future of a clinical success story

D Hirjak, G Fricchione, RC Wolf, G Northoff - Schizophrenia Research, 2024 - Elsevier
The effect of lorazepam in the treatment of catatonia is outstanding and almost immediate.
Clinicians are familiar with its effects: mute patients can speak again, akinetic patients can …

A narrative review of emotion regulation process in stress and recovery phases

PE Flores-Kanter, L Moretti, LA Medrano - Heliyon, 2021 - cell.com
The difficulty in studying the relationship between stress and emotional regulation is due to
the need to contemplate a dynamic perspective that analyzes the moderating role of stress …

The origins of catatonia–Systematic review of historical texts between 1800 and 1900

D Hirjak, JR Foucher, M Ams, LC Jeanjean… - Schizophrenia …, 2024 - Elsevier
Since January 1st 2022, catatonia is (again) recognized as an independent diagnostic entity
in the 11th revision of the International Classification of Diseases (ICD-11). This is a relevant …

FKBP51 mediates resilience to inflammation-induced anxiety through regulation of glutamic acid decarboxylase 65 expression in mouse hippocampus

YL Gan, CY Wang, RH He, PC Hsu, HH Yeh… - Journal of …, 2022 - Springer
Background Inflammation is a potential risk factor of mental disturbance. FKBP5 that
encodes FK506-binding protein 51 (FKBP51), a negative cochaperone of glucocorticoid …

Interaction between Oligodendrocytes and Interneurons in Brain Development and Related Neuropsychiatric Disorders

Y Liu, J Yuan, Y Dong, S Jiang, M Zhang… - International Journal of …, 2024 - mdpi.com
A variety of neurological and psychiatric disorders have recently been shown to be highly
associated with the abnormal development and function of oligodendrocytes (OLs) and …

Clinical characterization of brief psychotic disorders triggered by the COVID-19 pandemic: a multicenter observational study

MJ Valdés-Florido, A Lopez-Diaz… - European Archives of …, 2021 - Springer
This study aimed to characterize the clinical profile of patients with brief psychotic disorders
(BPD) triggered by the psychosocial distress derived from the COVID-19 crisis. A multicenter …

Catatonia

D Hirjak, JP Rogers, RC Wolf, KM Kubera… - Nature Reviews …, 2024 - nature.com
Catatonia is a neuropsychiatric disorder characterized by motor, affective and cognitive–
behavioural signs, which lasts from hours to days. Intensive research over the past two …