Aspergillus fumigatus is a saprotrophic fungus; its primary habitat is the soil. In its ecological
niche, the fungus has learned how to adapt and proliferate in hostile environments. This …

Covering: up to 2014 Siderophores are chelators synthesized by microbes to sequester iron.
This article summarizes the knowledge on the fungal siderophore metabolism with a focus …

Aspergillus fumigatus is an environmental saprobe and opportunistic human fungal
pathogen. Despite an estimated annual occurrence of more than 300,000 cases of invasive …

To maintain iron homeostasis, fungi have to balance iron acquisition, storage, and utilization
to ensure sufficient supply and to avoid toxic excess of this essential trace element. As …

The significant increase in the use of antifungal agents, both for the treatment of candidiasis
and invasive aspergillosis and as azole fungicides in agricultural crop protection has …

Since the first description of an azole-resistant A. fumigatus strain in 1997, there has been
an increasing number of papers describing the emergence of azole resistance. Firstly …

Azole compounds are the primary therapy for patients with diseases caused by Aspergillus
fumigatus. However, prolonged treatment may cause resistance to develop, which is …

Over the last 3 decades, the frequency of life-threatening human fungal infections has
increased as advances in medical therapies, solid-organ and hematopoietic stem cell …

The Aspergillus fumigatus sterol regulatory element binding protein (SREBP) SrbA belongs
to the basic Helix-Loop-Helix (bHLH) family of transcription factors and is crucial for …

Aspergillus fumigatus is a saprophytic, filamentous fungus found in soils and compost and
the causative agent of several pulmonary diseases in humans, birds, and other mammals. A …