Abstract The US Food and Drug Administration approval of the first 3D printed tablet in 2015
has ignited growing interest in 3D printing, or additive manufacturing (AM), for drug delivery …

Numerous cancer-associated deaths are owing to a lack of effective diagnostic and
therapeutic approaches. Microfluidic systems for analyzing a low volume of samples offer a …

Current in vitro antitumor drug screening strategies insufficiently mimic biological systems.
They tend to lack true perfusion and draining microcirculation systems, which may post …

An early step of metastasis requires a complex and coordinated migration of invasive tumor
cells into the surrounding tumor microenvironment (TME), which contains extracellular …

The discrepancies between the findings in preclinical studies, and in vivo testing and clinical
trials have resulted in the gradual decline in drug approval rates over the past decades …

Microfluidic devices have led to novel biological advances through the improvement of micro
systems that can mimic and measure. Microsystems easily handle sub-microliter volumes …

While there are many clinical drugs for prophylaxis and treatment, the search for those with
low or no risk of side effects for the control of infectious and non-infectious diseases is a …

Infectious outbreaks are the foremost global public health concern, challenging the current
healthcare system, which claims millions of lives annually. The most crucial way to control …

Despite the booming progress of anticancer nanomedicines in the past two decades,
precise tumor-targetability and sufficient tumor-accumulation are less successful and still …

The complexity of cancer biology and its clinical manifestation are driven by genetic,
epigenetic, transcriptomic, proteomic and metabolomic alterations, supported by genomic …