pH‐responsive polymers for drug delivery: trends and opportunities

J Singh, P Nayak - Journal of polymer science, 2023 - Wiley Online Library
Polymer science has applications in biomedical engineering, prosthetics, surgical implants,
and prospective pharmaceutical excipients for drug delivery.“Intelligent or Smart Polymers” …

Stimuli-responsive therapeutic metallodrugs

X Wang, X Wang, S **, N Muhammad, Z Guo - Chemical reviews, 2018 - ACS Publications
The success of platinum-based anticancer agents has motivated the exploration of novel
metal-based drugs for several decades, whereas problems such as drug-resistance and …

[HTML][HTML] Poly (N-isopropylacrylamide)-based thermoresponsive composite hydrogels for biomedical applications

X Xu, Y Liu, W Fu, M Yao, Z Ding, J Xuan, D Li, S Wang… - Polymers, 2020 - mdpi.com
Poly (N-isopropylacrylamide)(PNIPAM)-based thermosensitive hydrogels demonstrate great
potential in biomedical applications. However, they have inherent drawbacks such as low …

Mechanisms and biomaterials in pH-responsive tumour targeted drug delivery: A review

M Kanamala, WR Wilson, M Yang, BD Palmer, Z Wu - Biomaterials, 2016 - Elsevier
As the mainstay in the treatment of various cancers, chemotherapy plays a vital role, but still
faces many challenges, such as poor tumour selectivity and multidrug resistance (MDR) …

pH-sensitive biomaterials for drug delivery

S Zhuo, F Zhang, J Yu, X Zhang, G Yang, X Liu - Molecules, 2020 - mdpi.com
The development of precise and personalized medicine requires novel formulation
strategies to deliver the therapeutic payloads to the pathological tissues, producing …

Polymeric microneedles for transdermal protein delivery

Y Ye, J Yu, D Wen, AR Kahkoska, Z Gu - Advanced drug delivery reviews, 2018 - Elsevier
The intrinsic properties of therapeutic proteins generally present a major impediment for
transdermal delivery, including their relatively large molecule size and susceptibility to …

Manufactures of bio‐degradable and bio‐based polymers for bio‐materials in the pharmaceutical field

T Aziz, A Ullah, A Ali, M Shabeer… - Journal of Applied …, 2022 - Wiley Online Library
In recent years, bio‐based polymers have emerged as an alternative to petroleum‐based
polymers in various industries. The bio‐based materials are made from raw materials …

[HTML][HTML] Stimuli-responsive nanomaterials for application in antitumor therapy and drug delivery

SH Pham, Y Choi, J Choi - Pharmaceutics, 2020 - mdpi.com
The new era of nanotechnology has produced advanced nanomaterials applicable to
various fields of medicine, including diagnostic bio-imaging, chemotherapy, targeted drug …

Current trends of targeted therapy for oral squamous cell carcinoma

H Li, Y Zhang, M Xu, D Yang - Journal of cancer research and clinical …, 2022 - Springer
Oral squamous cell carcinoma (OSCC) is a malignant disease in the world which has a
profound effect on human health and life quality. According to tumor stage and pathological …

Enzyme-responsive hydrogels as potential drug delivery systems—state of knowledge and future prospects

M Sobczak - International journal of molecular sciences, 2022 - mdpi.com
Fast advances in polymer science have provided new hydrogels for applications in drug
delivery. Among modern drug formulations, polymeric type stimuli-responsive hydrogels …