The therapeutic potential of naringenin: a review of clinical trials

B Salehi, PVT Fokou, M Sharifi-Rad, P Zucca… - Pharmaceuticals, 2019 - mdpi.com
Naringenin is a flavonoid belonging to flavanones subclass. It is widely distributed in several
Citrus fruits, bergamot, tomatoes and other fruits, being also found in its glycosides form …

Plant phenolics: Bioavailability as a key determinant of their potential health-promoting applications

P Cosme, AB Rodríguez, J Espino, M Garrido - Antioxidants, 2020 - mdpi.com
Phenolic compounds are secondary metabolites widely spread throughout the plant
kingdom that can be categorized as flavonoids and non-flavonoids. Interest in phenolic …

Inhibition of SARS-CoV 3CL protease by flavonoids

S Jo, S Kim, DH Shin, MS Kim - Journal of enzyme inhibition and …, 2020 - Taylor & Francis
There were severe panics caused by Severe Acute Respiratory Syndrome (SARS) and
Middle-East Respiratory Syndrome-Coronavirus. Therefore, researches targeting these …

Naringenin, a flavanone with antiviral and anti‐inflammatory effects: A promising treatment strategy against COVID‐19

H Tutunchi, F Naeini, A Ostadrahimi… - Phytotherapy …, 2020 - Wiley Online Library
At the end of 2019, a novel flu‐like coronavirus named COVID‐19 (coronavirus disease
2019) was recognized by World Health Organization. No specific treatments exist for COVID …

Characteristics of flavonoids as potent MERS‐CoV 3C‐like protease inhibitors

S Jo, H Kim, S Kim, DH Shin… - Chemical biology & drug …, 2019 - Wiley Online Library
Middle East respiratory syndrome‐coronavirus (MERS‐CoV) is a zoonotic virus transmitted
between animals and human beings. It causes MERS with high mortality rate. However, no …

Revealing the potency of citrus and galangal constituents to halt SARS-CoV-2 infection

RY Utomo, M Ikawati, E Meiyanto - 2020 - preprints.org
COVID-19 pandemic is a serious problem in the world today. The SARS-CoV-2 virus that
causes COVID-19 has important proteins used for its infection and development, namely the …

Flavonoids as Antiviral Agents for Enterovirus A71 (EV-A71)

S Lalani, CL Poh - Viruses, 2020 - mdpi.com
Flavonoids are natural biomolecules that are known to be effective antivirals. These
biomolecules can act at different stages of viral infection, particularly at the molecular level to …

SARS-CoV-2 and the host cell: a tale of interactions

M Pizzato, C Baraldi, G Boscato Sopetto… - Frontiers in …, 2022 - frontiersin.org
The ability of a virus to spread between individuals, its replication capacity and the clinical
course of the infection are macroscopic consequences of a multifaceted molecular …

In silico pharmacokinetic and molecular docking studies of natural flavonoids and synthetic indole chalcones against essential proteins of SARS-CoV-2

BG Vijayakumar, D Ramesh, A Joji, T Kannan - European journal of …, 2020 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is distinctly infective and
there is an ongoing effort to find a cure for this pandemic. Flavonoids exist in many diets as …

Natural molecules in the management of polycystic ovary syndrome (PCOS): an analytical review

M Iervolino, E Lepore, G Forte, AS Laganà… - Nutrients, 2021 - mdpi.com
Polycystic ovary syndrome (PCOS) is a heterogenous disorder characterized by chronic
ovulation dysfunction and hyperandrogenism. It is considered the most common …