Microbiome breeding: conceptual and practical issues

UG Mueller, TA Linksvayer - Trends in microbiology, 2022 - cell.com
Microbiome breeding is a new artificial selection technique that seeks to change the genetic
composition of microbiomes in order to benefit plant or animal hosts. Recent experimental …

A tale of two diseases: Exploring mechanisms linking diabetes mellitus with Alzheimer's disease

J Lynn, M Park, C Ogunwale… - Journal of …, 2022 - journals.sagepub.com
Dementias, including the type associated with Alzheimer's disease (AD), are on the rise
worldwide. Similarly, type 2 diabetes mellitus (T2DM) is one of the most prevalent chronic …

Ginseng under forest exerts stronger anti-aging effects compared to garden ginseng probably via regulating PI3K/AKT/mTOR pathway, SIRT1/NF-κB pathway and …

M Hao, C Ding, X Peng, H Chen, L Dong, Y Zhang… - Phytomedicine, 2022 - Elsevier
Background Ginseng is deemed to be an effective anti-aging therapy. Evidence for
differences in representative active ingredients and anti-aging effects between garden …

Emerging epigenetic dynamics in gut-microglia brain axis: experimental and clinical implications for accelerated brain aging in schizophrenia

B Ben-Azu, EC Del Re, J VanderZwaag… - Frontiers in Cellular …, 2023 - frontiersin.org
Brain aging, which involves a progressive loss of neuronal functions, has been reported to
be premature in probands affected by schizophrenia (SCZ). Evidence shows that SCZ and …

Gut microbiome–immune system interaction in reptiles

R Siddiqui, SK Maciver, NA Khan - Journal of Applied …, 2022 - academic.oup.com
Reptiles are ectothermic amniotes in a world dominated by endotherms. Reptiles originated
more than 300 million years ago and they often dwell in polluted environments which may …

Gut-brain axis and neurodegeneration: Mechanisms and therapeutic potentials

KJ Park, Y Gao - Frontiers in Neuroscience, 2024 - frontiersin.org
This paper reviews the effects of gut microbiota in regulating neurodegenerative diseases
through controlling gut-brain axis. Specific microbial populations and their metabolites (short …

Age-related diseases, therapies and gut microbiome: A new frontier for healthy aging

M Barone, F D'Amico, S Rampelli, P Brigidi… - Mechanisms of Ageing …, 2022 - Elsevier
The gut microbiome is undoubtedly a key modulator of human health, which can promote or
impair homeostasis throughout life. This is even more relevant in old age, when there is a …

Chitosan-modified Phellinus igniarius polysaccharide PLGA nanoparticles ameliorated inflammatory bowel disease

X Bai, Z Feng, S Peng, T Zhu, L Jiao, N Mao, P Gu… - Biomaterials …, 2022 - Elsevier
In many clinical studies, prebiotics have been used as adjuvant therapy for inflammatory
bowel disease (IBD). Phellinus igniarius polysaccharide (PIP) possesses great anti …

Longevity, cellular senescence and the gut microbiome: Lessons to be learned from crocodiles

R Siddiqui, S Maciver, A Elmoselhi, NC Soares… - Heliyon, 2021 - cell.com
Crocodiles are flourishing large-bodied ectotherms in a world dominated by endotherms.
They survived the Cretaceous extinction event, that eradicated the dinosaurs who are …

[HTML][HTML] The senotherapeutic potential of phytochemicals for age-related intestinal disease

CM Costa, SS Pedrosa, JL Kirkland, F Reis… - Ageing Research …, 2025 - Elsevier
During the last few decades, life expectancy has increased worldwide along with the
prevalence of several age-related diseases. Among aging pathways, cellular senescence …