Sensitivity analysis approaches applied to systems biology models

Z Zi - IET systems biology, 2011 - IET
With the rising application of systems biology, sensitivity analysis methods have been widely
applied to study the biological systems, including metabolic networks, signalling pathways …

Autogenerating microsecond solvers for nonlinear MPC: a tutorial using ACADO integrators

R Quirynen, M Vukov, M Zanon… - … Control Applications and …, 2015 - Wiley Online Library
Nonlinear model predictive control (NMPC) allows one to explicitly treat nonlinear dynamics
and constraints. To apply NMPC in real time on embedded hardware, online algorithms as …

On neural differential equations

P Kidger - arxiv preprint arxiv:2202.02435, 2022 - arxiv.org
The conjoining of dynamical systems and deep learning has become a topic of great
interest. In particular, neural differential equations (NDEs) demonstrate that neural networks …

Human In Silico Drug Trials Demonstrate Higher Accuracy than Animal Models in Predicting Clinical Pro-Arrhythmic Cardiotoxicity

E Passini, OJ Britton, HR Lu, J Rohrbacher… - Frontiers in …, 2017 - frontiersin.org
Early prediction of cardiotoxicity is critical for drug development. Current animal models
raise ethical and translational questions, and have limited accuracy in clinical risk prediction …

ChemNODE: A neural ordinary differential equations framework for efficient chemical kinetic solvers

O Owoyele, P Pal - Energy and AI, 2022 - Elsevier
Solving for detailed chemical kinetics remains one of the major bottlenecks for
computational fluid dynamics simulations of reacting flows using a finite-rate-chemistry …

Enabling new flexibility in the SUNDIALS suite of nonlinear and differential/algebraic equation solvers

DJ Gardner, DR Reynolds, CS Woodward… - ACM Transactions on …, 2022 - dl.acm.org
In recent years, the SUite of Nonlinear and DIfferential/ALgebraic equation Solvers
(SUNDIALS) has been redesigned to better enable the use of application-specific and third …

SUNDIALS: Suite of nonlinear and differential/algebraic equation solvers

AC Hindmarsh, PN Brown, KE Grant, SL Lee… - ACM Transactions on …, 2005 - dl.acm.org
SUNDIALS is a suite of advanced computational codes for solving large-scale problems that
can be modeled as a system of nonlinear algebraic equations, or as initial-value problems in …

Computational characterization of hydrogen direct injection and nonpremixed combustion in a compression-ignition engine

R Babayev, A Andersson, AS Dalmau, HG Im… - International Journal of …, 2021 - Elsevier
With the revived interest in hydrogen (H 2) as a direct combustion fuel for engine
applications, a computational study is conducted to assess the characteristics of H 2 direct …

Evaluating model predictive path following and yaw stability controllers for over-actuated autonomous electric vehicles

W Zhang, Z Wang, L Drugge… - IEEE Transactions on …, 2020 - ieeexplore.ieee.org
Active safety systems are of significant importance for autonomous vehicles operating in
safety-critical situations like an obstacle-avoidance manoeuvre with high vehicle speed or …

Inferring latent dynamics underlying neural population activity via neural differential equations

TD Kim, TZ Luo, JW Pillow… - … Conference on Machine …, 2021 - proceedings.mlr.press
An important problem in systems neuroscience is to identify the latent dynamics underlying
neural population activity. Here we address this problem by introducing a low-dimensional …