Recent advances in bioactive pyrazoles

ŞG Küçükgüzel, S Şenkardeş - European Journal of Medicinal Chemistry, 2015 - Elsevier
Pyrazole is a five membered and two-nitrogen containing heterocyclic ring. These structures
have been investigated in the development of novel compounds with hypoglycemic …

Current status of pyrazole and its biological activities

MJ Naim, O Alam, F Nawaz, MJ Alam… - Journal of Pharmacy …, 2016 - journals.lww.com
Pyrazole are potent medicinal scaffolds and exhibit a full spectrum of biological activities.
This review throws light on the detailed synthetic approaches which have been applied for …

Recent advancement in drug design and discovery of pyrazole biomolecules as cancer and inflammation therapeutics

MJ Alam, O Alam, MJ Naim, F Nawaz, A Manaithiya… - Molecules, 2022 - mdpi.com
Pyrazole, an important pharmacophore and a privileged scaffold of immense significance, is
a five-membered heterocyclic moiety with an extensive therapeutic profile, viz., anti …

Recent developments in azole compounds as antibacterial and antifungal agents

XM Peng, GX Cai, CH Zhou - Current Topics in Medicinal …, 2013 - ingentaconnect.com
Azole compounds are an important class of nitrogen heterocycles with electron-rich
property. This special structure endows azole-based derivatives easily bind with the …

Novel benzoic acid derivatives: Synthesis and biological evaluation as multitarget acetylcholinesterase and carbonic anhydrase inhibitors

M Kalaycı, C Türkeş, M Arslan, Y Demir… - Archiv der …, 2021 - Wiley Online Library
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by dementia,
memory impairment, cognitive dysfunction, and speech impairment. The utility of cholinergic …

Hydrothermal preparation and characterization of ZnFe2O4 magnetic nanoparticles as an efficient heterogeneous catalyst for the synthesis of multi‐substituted …

AA Marzouk, AM Abu‐Dief… - Applied Organometallic …, 2018 - Wiley Online Library
Nanoparticles are key focus of research for a wide range of novel applications. As such,
ZnFe2O4 magnetic nanoparticles were synthesized hydrothermally and characterized via …

[PDF][PDF] A review on pyrazole chemical entity and biological activity

MJ Alam, O Alam, P Alam, MJ Naim - Int. J. Pharm. Sci. Res, 2015 - ijpsr.info
Aromatic organic heterocycle containing pyrimidine scaffolds possesses two nitrogen atoms
of Five-membered ring. These Pyrazole skeletons comprise various ranges of …

Synthesis of novel oxime-containing pyrazole derivatives and discovery of regulators for apoptosis and autophagy in A549 lung cancer cells

LW Zheng, Y Li, D Ge, BX Zhao, YR Liu, HS Lv… - Bioorganic & medicinal …, 2010 - Elsevier
A series of novel oxime-containing pyrazole derivatives were synthesized by the reaction of
ethyl 3-phenyl-1H-pyrazole-5-carboxylate derivatives and 2-bromo-1-phenylethanone …

Novel 1-[4-(Aminosulfonyl) phenyl]-1H-1, 2, 4-triazole derivatives with remarkable selective COX-2 inhibition: Design, synthesis, molecular docking, anti-inflammatory …

GEDAA Abuo-Rahma, M Abdel-Aziz, NA Farag… - European journal of …, 2014 - Elsevier
Abstract A novel series of 1, 2, 4-triazole derivatives were synthesized and confirmed with
different spectroscopic techniques. The prepared compounds exhibited remarkable anti …

Experimental and theoretical investigations for some spiropyrazoles derivatives as corrosion inhibitors for copper in 2 M HNO3 solutions

HS Gadow, TA Farghaly, AM Eldesoky - Journal of Molecular Liquids, 2019 - Elsevier
Rates of corrosion for copper were monitored in aerated stagnant 2 M HNO 3 solutions at
different temperatures (25-55° C) using Tafel extrapolation method, electrochemical …