The most definitive classification systems for dementia are based on the underlying
pathology which, in turn, is categorized largely according to the observed accumulation of …

Frontotemporal lobar degeneration (FTLD) is a clinically and pathologically heterogeneous
syndrome, characterized by progressive decline in behaviour or language associated with …

Objective: To identify rates of and risk factors for psychiatric diagnosis preceding the
diagnosis of neurodegenerative disease. Method: Systematic, retrospective, blinded chart …

Disruptions in emotional, cognitive, and social behavior are common in neurodegenerative
disease and in many forms of psychopathology. Because neurodegenerative diseases have …

Frontotemporal dementia was documented over a century ago. The last decade, however,
has seen substantial changes in our conceptions of this increasingly recognized disorder …

“Ms. A,” a 46-year-old woman, was referred for inpatient treatment at the Obsessive-
Compulsive Disorder Institute (OCDI) of McLean Hospital (Belmont, Mass.). She had no prior …

Objectives Approximately 3.5 million Americans will experience a manic episode during
their lifetimes. The most common causes are psychiatric illnesses such as bipolar I disorder …

Positive emotions foster social relationships and motivate thought and action. Dysregulation
of positive emotion may give rise to debilitating clinical symptomatology such as mania, risk …

Objective: To evaluate the cause of diagnostic errors in the visual interpretation of positron
emission tomographic scans with fludeoxyglucose F 18 (FDG-PET) in patients with …

It is a common pathway for patients with the behavioral variant of frontotemporal dementia
(bvFTD) to be first misdiagnosed with a primary psychiatric disorder, a considerable …