Developmental neurotoxicity of succeeding generations of insecticides

Y Abreu-Villaça, ED Levin - Environment international, 2017 - Elsevier
Insecticides are by design toxic. They must be toxic to effectively kill target species of insects.
Unfortunately, they also have off-target toxic effects that can harm other species, including …

Effects of monoterpenes on ion channels of excitable cells

M Oz, Y Lozon, A Sultan, KHS Yang… - Pharmacology & …, 2015 - Elsevier
Monoterpenes are a structurally diverse group of phytochemicals and a major constituent of
plant-derived 'essential oils'. Monoterpenes such as menthol, carvacrol, and eugenol have …

[HTML][HTML] Adverse effects of bifenthrin exposure on neurobehavior and neurodevelopment in a zebrafish embryo/larvae model

K Eghan, S Lee, D Yoo, CH Kim, WK Kim - Chemosphere, 2023 - Elsevier
Bifenthrin, a third-generation synthetic pyrethroid, is widely used as an agricultural
insecticide. However, it can flow into surface and groundwater, leading to adverse …

A prospective study of environmental exposures and early biomarkers in autism spectrum disorder: design, protocols, and preliminary data from the MARBLES study

I Hertz-Picciotto, RJ Schmidt, CK Walker… - Environmental …, 2018 - ehp.niehs.nih.gov
Background: Until recently, environmental factors in autism spectrum disorder (ASD) were
largely ignored. Over the last decade, altered risks from lifestyle, medical, chemical, and …

In utero pyrethroid pesticide exposure in relation to autism spectrum disorder (ASD) and other neurodevelopmental outcomes at 3 years in the MARBLES longitudinal …

JM Barkoski, C Philippat, D Tancredi, RJ Schmidt… - Environmental …, 2021 - Elsevier
Background We assessed the relationships between prenatal pyrethroid pesticide exposure
and autism spectrum disorders (ASD) or non-typical development (non-TD) at 3 years …

Inflammatory and oxidative mechanisms potentiate bifenthrin-induced neurological alterations and anxiety-like behavior in adult rats

B Gargouri, HS Bhatia, M Bouchard, BL Fiebich… - Toxicology letters, 2018 - Elsevier
Bifenthrin (BF) is a synthetic pyrethroid pesticide widely used in several countries to manage
insect pests on diverse agricultural crops. Growing evidence indicates that BF exposure is …

Bifenthrin causes transcriptomic alterations in mTOR and ryanodine receptor-dependent signaling and delayed hyperactivity in develo** zebrafish (Danio rerio)

DF Frank, GW Miller, DJ Harvey, SM Brander, J Geist… - Aquatic toxicology, 2018 - Elsevier
Over the last few decades, the pyrethroid insecticide bifenthrin has been increasingly
employed for pest control in urban and agricultural areas, putting humans and wildlife at …

Bifenthrin exposure causes hyperactivity in early larval stages of an endangered fish species at concentrations that occur during their hatching season

PC Mundy, MF Carte, SM Brander, TC Hung… - Aquatic Toxicology, 2020 - Elsevier
Bifenthrin is a pyrethroid insecticide commonly used in agricultural and urban sectors, and is
found in watersheds worldwide. As a sodium channel blocker, at sublethal concentrations it …

Metabolomic Profiles in the Brains of Juvenile Steelhead (Oncorhynchus mykiss) Following Bifenthrin Treatment

JT Magnuson, Z Cryder, NE Andrzejczyk… - … science & technology, 2020 - ACS Publications
The pyrethroid insecticide, bifenthrin, is frequently measured at concentrations exceeding
those that induce acute and chronic toxicity to several invertebrate and fish species residing …

Investigations into hydrogen sulfide-induced suppression of neuronal activity in vivo and calcium dysregulation in vitro

DS Kim, IN Pessah, CM Santana… - Toxicological …, 2023 - academic.oup.com
Acute exposure to high concentrations of hydrogen sulfide (H2S) leads to sudden death
and, if survived, lingering neurological disorders. Clinical signs include seizures, loss of …