The Endocannabinoid System (ECS) is primarily responsible for maintaining homeostasis, a
balance in internal environment (temperature, mood, and immune system) and energy input …

Background and aim Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory
disease; the clinical manifestations are correlated with continuum multiarticular synovitis …

The immune response of the host towards foreign body, especially in the form of giant cell
reaction against the implanted materials, is a vital factor for determining the repair outcome …

Bone endoprosthesis in patients with systemic chronic inflammation frequently leads to poor
osseointegration after implantation mainly due to the increase in pro-inflammatory cytokines …

The emergence of inflammatory diseases is a heavy burden on modern societies. Cannabis
has been used for several millennia to treat inflammatory disorders such as rheumatism or …

The homeostasis of bone microenvironment is the foundation of bone health and comprises
2 concerted events: bone formation by osteoblasts and bone resorption by osteoclasts. In …

Harpagophytum procumbens subsp. procumbens (Burch.) DC. ex Meisn.(Sesame seed
Family—Pedaliaceae) is a popular medicinal plant known as Devil's claw. It is …

Activation state of synovial macrophages is significantly correlated with disease activity and
severity of rheumatoid arthritis (RA) and provides valuable clues for RA treatment …

The endocannabinoid system has attracted attention as a pharmacological target for several
pathological conditions. Cannabinoid (CB2)-selective agonists have been the focus of …

Under diabetic conditions, blood glucose fluctuations and exacerbated immunopathological
inflammatory environments pose significant challenges to periosteal regenerative repair …