Surfactants are a diverse group of compounds that share the capacity to adsorb at the
boundary between distinct phases of matter. They are used as pharmaceutical excipients …

Despite the promising prospects of nanoparticles in oral drug delivery, the process of oral
administration involves a complex transportation pathway that includes cellular uptake …

Exemestane (EXE) a potent third generation aromatase inhibitor and is employed as first
line treatment in estrogen receptor positive breast cancer. Its oral bioavailability is only 5 …

Glioblastoma (GBM) recurrences appear in most cases around the resection cavity borders
and arise from residual GBM cells that cannot be removed by surgery. Here, we propose a …

Epilepsy is a highly prevalent neurological disease and valproic acid (VPA) is used as a first-
line chronic treatment. However, this drug has poor oral bioavailability, which requires the …

Introduction Diabetes mellitus is one of the challenging health problems worldwide. Multiple
daily subcutaneous injection of insulin causes poor compliance in patients. Development of …

Donepezil hydrochloride (DPL) and Embelin (EMB) loaded Nanostructured Lipid Carriers
(NLCs) have been developed and optimized to achieve optimal drug loading, safer nasal …

Introduction Self-emulsifying drug delivery systems (SEDDS) are a promising strategy to
improve the oral bioavailability of poorly water-soluble drugs (PWSD). However, poor drug …

This study aimed to develop oral lipidic hybrids of amikacin sulfate (AMK), incorporating
thiolated chitosan as a P-glycoprotein (P-gp) inhibitor to enhance intestinal absorptivity and …

This study focuses on optimizing the delivery of Nelfinavir (NFV), a vital protease inhibitor in
antiretroviral therapy, and Epigallocatechin gallate (EGCG), a potent adjunctive anti-human …