HIV as a cause of immune activation and immunosenescence
Systemic immune activation has emerged as an essential component of the
immunopathogenesis of HIV. It not only leads to faster disease progression, but also to …
immunopathogenesis of HIV. It not only leads to faster disease progression, but also to …
[HTML][HTML] IP-10 is highly involved in HIV infection
J Lei, X Yin, H Shang, Y Jiang - Cytokine, 2019 - Elsevier
Abstract Interferon-γ (IFN-γ)-induced protein 10 (IP-10 or CXCL-10) is a chemokine involved
in trafficking immune cells to inflammatory sites. Numerous studies have reported …
in trafficking immune cells to inflammatory sites. Numerous studies have reported …
The role of transforming growth factor beta-1 in the progression of HIV/AIDS and development of non-AIDS-defining fibrotic disorders
AJ Theron, R Anderson, TM Rossouw… - Frontiers in …, 2017 - frontiersin.org
Even after attainment of sustained viral suppression following implementation of highly
active antiretroviral therapy, HIV-infected persons continue to experience persistent, low …
active antiretroviral therapy, HIV-infected persons continue to experience persistent, low …
Pro-inflammatory cytokine levels in HIV infected and uninfected pregnant women with and without preeclampsia
Introduction Preeclampsia and HIV/AIDS are inflammatory conditions that contribute
significantly to adverse maternal and foetal outcomes. The immune reconstitution effects of …
significantly to adverse maternal and foetal outcomes. The immune reconstitution effects of …
Influence of immune activation and inflammatory response on cardiovascular risk associated with the human immunodeficiency virus
Patients infected with the human immunodeficiency virus (HIV) have an increased
cardiovascular risk. Although initially this increased risk was attributed to metabolic …
cardiovascular risk. Although initially this increased risk was attributed to metabolic …
Cytokines and persistent viral infections
JC Beltra, H Decaluwe - Cytokine, 2016 - Elsevier
Intracellular pathogens such as the human immunodeficiency virus, hepatitis C and B or
Epstein–Barr virus often cause chronic viral infections in humans. Persistence of these …
Epstein–Barr virus often cause chronic viral infections in humans. Persistence of these …
Dynamics of transforming growth factor (TGF)-β superfamily cytokine induction during HIV-1 infection are distinct from other innate cytokines
M Dickinson, AE Kliszczak, E Giannoulatou… - Frontiers in …, 2020 - frontiersin.org
Human immunodeficiency virus type 1 (HIV-1) infection triggers rapid induction of multiple
innate cytokines including type I interferons, which play important roles in viral control and …
innate cytokines including type I interferons, which play important roles in viral control and …
Plasma biomarkers of human immunodeficiency virus–related systemic inflammation and immune activation in Sub-Saharan Africa before and during suppressive …
S Kroeze, FW Wit, TM Rossouw… - The Journal of …, 2019 - academic.oup.com
We evaluated immune biomarker profiles in human immunodeficiency virus (HIV)–infected
adults (n= 398) from 5 African countries. Although all biomarkers decreased after …
adults (n= 398) from 5 African countries. Although all biomarkers decreased after …
Alzheimer's-like pathology at the crossroads of hiv-associated neurological disorders
Despite the widespread success of combined antiretroviral therapy (cART) in suppressing
viremia, the prevalence of human immunodeficiency virus (HIV)-associated neurological …
viremia, the prevalence of human immunodeficiency virus (HIV)-associated neurological …
Targeting TNF-alpha in HIV-1 infection
Highly active antiretroviral therapy (HAART) has dramatically extended the lifespan and
quality of life of individuals infected with human immunodeficiency virus type 1 (HIV-1) …
quality of life of individuals infected with human immunodeficiency virus type 1 (HIV-1) …