The cognitive map in humans: spatial navigation and beyond

RA Epstein, EZ Patai, JB Julian, HJ Spiers - Nature neuroscience, 2017 - nature.com
The'cognitive map'hypothesis proposes that brain builds a unified representation of the
spatial environment to support memory and guide future action. Forty years of …

Scene perception in the human brain

RA Epstein, CI Baker - Annual review of vision science, 2019 - annualreviews.org
Humans are remarkably adept at perceiving and understanding complex real-world scenes.
Uncovering the neural basis of this ability is an important goal of vision science …

The occipital place area is causally involved in representing environmental boundaries during navigation

JB Julian, J Ryan, RH Hamilton, RA Epstein - Current Biology, 2016 - cell.com
Thirty years of research suggests that environmental boundaries—eg, the walls of an
experimental chamber or room—exert powerful influence on navigational behavior, often to …

The neurocognitive basis of spatial reorientation

JB Julian, AT Keinath, SA Marchette, RA Epstein - Current Biology, 2018 - cell.com
The ability to recover one's bearings when lost is a skill that is fundamental for spatial
navigation. We review the cognitive and neural mechanisms that underlie this ability, with …

Multiple maps of the same spatial context can stably coexist in the mouse hippocampus

L Sheintuch, N Geva, H Baumer, Y Rechavi, A Rubin… - Current biology, 2020 - cell.com
Hippocampal place cells selectively fire when an animal traverses a particular location and
are considered a neural substrate of spatial memory. Place cells were shown to change their …

A novel virtual reality-based training protocol for the enhancement of the “mental frame syncing” in individuals with Alzheimer's disease: a development-of-concept trial

S Serino, E Pedroli, C Tuena, G De Leo… - Frontiers in aging …, 2017 - frontiersin.org
A growing body of evidence suggests that people with Alzheimer's Disease (AD) show
compromised spatial abilities. In addition, there exists from the earliest stages of AD a …

The basis of navigation across species

CA Freas, K Cheng - Annual review of psychology, 2022 - annualreviews.org
Animals navigate a wide range of distances, from a few millimeters to globe-spanning
journeys of thousands of kilometers. Despite this array of navigational challenges, similar …

Landmark-based spatial navigation across the human lifespan

M Bécu, D Sheynikhovich, S Ramanoël, G Tatur… - ELife, 2023 - elifesciences.org
Human spatial cognition has been mainly characterized in terms of egocentric (body-
centered) and allocentric (world-centered) wayfinding behavior. It was hypothesized that …

Environmental geometry aligns the hippocampal map during spatial reorientation

AT Keinath, JB Julian, RA Epstein, IA Muzzio - Current Biology, 2017 - cell.com
When a navigator's internal sense of direction is disrupted, she must rely on external cues to
regain her bearings, a process termed spatial reorientation. Extensive research has …

Electrophysiological signatures of spatial boundaries in the human subiculum

SA Lee, JF Miller, AJ Watrous, MR Sperling… - Journal of …, 2018 - jneurosci.org
Environmental boundaries play a crucial role in spatial navigation and memory across a
wide range of distantly related species. In rodents, boundary representations have been …