Brain-derived neurotrophic factor (BDNF) is one of the most distributed and extensively
studied neurotrophins in the mammalian brain. BDNF signals through the tropomycin …

As one of most common and severe mental disorders, major depressive disorder (MDD)
significantly increases the risks of premature death and other medical conditions for patients …

Brain-derived neurotrophic factor (BDNF) is one of the most studied neurotrophins in the
healthy and diseased brain. As a result, there is a large body of evidence that associates …

This is the first systematic review of the safety of ketamine in the treatment of depression
after single and repeated doses. We searched MEDLINE, PubMed, PsycINFO, and …

Depression is a major health problem with a high prevalence and a heavy socioeconomic
burden in western societies. It is associated with atrophy and impaired functioning of cortico …

Levels of brain-derived neurotrophic factor (BDNF) are reduced in the brain and serum of
depressed patients and at least the reduction in serum levels is reversible upon successful …

Serotonergic psychedelics are emerging as potential antidepressant therapeutic tools, as
suggested in a recent randomized controlled trial with ayahuasca for treatment-resistant …

Multiple lines of evidence have implicated brain-derived neurotrophic factor (BDNF) in
treatment-resistant depression (TRD). The aim of this synthesis was to determine the impact …

Purpose The accruing data linking the gut microbiome to the development and function of
the central nervous system has been proposed as a paradigm shift in neuroscience. The gut …

Abstract (R, S)-ketamine (ketamine) and its enantiomer (S)-ketamine (esketamine) can
produce rapid and substantial antidepressant effects. However, individual response to …