The ambitious and exciting Global Programme to Eliminate Lymphatic Filariasis (GPELF) is
largely based on a strategy of mass drug administration (MDA) of repeated rounds of …

Diagnostic tools appropriate for undertaking interventions to control helminth infections are
key to their success. Many diagnostic tests for helminth infection have unsatisfactory …

Antigen testing is now recognized as the method of choice for detection of Wuchereria
bancrofti infections. Unlike tests that detect microfilariae, antigen tests can be performed with …

Background. Available treatments for lymphatic filariasis (LF) are limited in their longterm
clearance of microfilaria from the blood. The safety and efficacy of a single-dose triple-drug …

Infants and children are routinely vaccinated with bacillus Calmette-Guérin (BCG) in areas of
the world where worm infections are common. Because maternal helminth infection during …

Chemotherapy of onchocerciasis by doxycycline, which targets symbiotic Wolbachia
endobacteria, has been shown to result in a long-term sterility of adult female worms and …

Lymphatic filariasis (LF), already recognized as a widespread, seriously handicap**
disease of adults, was generally thought to occur only sporadically in children. New, highly …

Lymphatic filariasis has afflicted people in the tropical areas of the world for thousands of
years but even up to comparatively recent times it has been poorly understood and its …

This review starts with discussions of several infectious causes of eosinophilic pneumonia,
which are almost exclusively parasitic in nature. Pulmonary infections due specifically to …

The development of antifilarial antibody responses is a characteristic feature of infection with
filarial parasites. It should be possible to exploit this fact to develop tools to monitor the …