Mitochondrial membrane potential

LD Zorova, VA Popkov, EY Plotnikov, DN Silachev… - Analytical …, 2018 - Elsevier
The mitochondrial membrane potential (ΔΨm) generated by proton pumps (Complexes I, III
and IV) is an essential component in the process of energy storage during oxidative …

The effects of plant flavonoids on mammalian cells: implications for inflammation, heart disease, and cancer

E Middleton Jr, C Kandaswami… - Pharmacological reviews, 2000 - Elsevier
Flavonoids are nearly ubiquitous in plants and are recognized as the pigments responsible
for the colors of leaves, especially in autumn. They are rich in seeds, citrus fruits, olive oil …

The role of mitochondria in apoptosis

C Wang, RJ Youle - Annual review of genetics, 2009 - annualreviews.org
Mitochondria play key roles in activating apoptosis in mammalian cells. Bcl-2 family
members regulate the release of proteins from the space between the mitochondrial inner …

Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex I

MY El-Mir, V Nogueira, E Fontaine, N Avéret… - Journal of Biological …, 2000 - ASBMB
We report here a new mitochondrial regulation occurring only in intact cells. We have
investigated the effects of dimethylbiguanide on isolated rat hepatocytes, permeabilized …

Etiology and pathogenesis of Parkinson's disease

CW Olanow, WG Tatton - Annual review of neuroscience, 1999 - annualreviews.org
▪ Abstract Parkinson's disease (PD) is an age-related neurodegenerative disorder that
affects approximately 1 million persons in the United States. It is characterized by resting …

[HTML][HTML] The mitochondrial permeability transition in cell death: a common mechanism in necrosis, apoptosis and autophagy

JJ Lemasters, AL Nieminen, T Qian, LC Trost… - … et Biophysica Acta (BBA …, 1998 - Elsevier
Using confocal microscopy, onset of the mitochondrial permeability transition (MPT) in
individual mitochondria within living cells can be visualized by the redistribution of the …

Mitochondrial control of apoptosis

G Kroemer, N Zamzami, SA Susin - Immunology today, 1997 - cell.com
The apoptotic process can be subdivided into three phases: a death-stimulus-dependent,
heterogeneous induction phase, a common effector phase during which the 'decision to …

Mitochondrial reactive oxygen species in cell death signaling

C Fleury, B Mignotte, JL Vayssière - Biochimie, 2002 - Elsevier
During apoptosis, mitochondrial membrane permeability (MMP) increases and the release
into the cytosol of pro-apoptotic factors (procaspases, caspase activators and caspase …

Superoxide production by the mitochondrial respiratory chain

JF Turrens - Bioscience reports, 1997 - Springer
Superoxide Production by the Mitochondrial Respiratory Chain Page 1 Bioscience Reports,
Vol. 17, No. 1, 1997 REVIEW Superoxide Production by the Mitochondrial Respiratory …

Mitochondrial control of nuclear apoptosis.

N Zamzami, SA Susin, P Marchetti, T Hirsch… - The Journal of …, 1996 - rupress.org
Anucleate cells can be induced to undergo programmed cell death (PCD), indicating the
existence of a cytoplasmic PCD pathway that functions independently from the nucleus …