Osteosarcoma is the most common primary malignant bone tumor and is associated with a
high risk of recurrence and distant metastasis. Effective treatment for osteosarcoma …

The survival rate for metastatic osteosarcoma has not improved for several decades, since
the introduction and refinement of chemotherapy as a treatment in addition to surgery. Over …

Background Osteosarcoma (OS) is the most common primary bone tumor in children and
adolescent. Surgery and multidrug chemotherapy are the standard of treatment achieving 60 …

Osteosarcoma is the most common bone malignancy in children and adolescents.
Conventional therapies include surgery, chemotherapy, and radiotherapy, which present …

Platinum (Pt II)-based anticancer agents exhibit a lack of selectivity in the treatment of
osteosarcoma, resulting in significant toxicity. Furthermore, immune surveillance withinthe …

Deep learning is a subfield of state-of-the-art artificial intelligence (AI) technology, and
multiple deep learning-based AI models have been applied to musculoskeletal diseases …

Osteosarcoma (OS) is the most common primary malignant bone tumor that mainly affects
the pediatric and adolescent population; limb salvage treatment has become one of the most …

Osteosarcoma (OS) is a pediatric malignant bone tumor that predominantly affects
adolescent and young adults. It has high risk for relapse and over the last four decades no …

Hypoxia-induced decrease in cisplatin (CDDP) sensitivity in human osteosarcoma (OS) is a
significant obstacle to effective chemotherapy. Recently, mitophagy has been shown to be …

Osteosarcoma, a rare primary bone cancer, presents diverse molecular aberrations that
underscore its complexity. Despite the persistent endeavors by researchers, the limited …