De novo metalloprotein design
Natural metalloproteins perform many functions—ranging from sensing to electron transfer
and catalysis—in which the position and property of each ligand and metal are dictated by …
and catalysis—in which the position and property of each ligand and metal are dictated by …
Type V secretion systems: an overview of passenger domain functions
I Meuskens, A Saragliadis, JC Leo… - Frontiers in microbiology, 2019 - frontiersin.org
Bacteria secrete proteins for different purposes such as communication, virulence functions,
adhesion to surfaces, nutrient acquisition, or growth inhibition of competing bacteria. For …
adhesion to surfaces, nutrient acquisition, or growth inhibition of competing bacteria. For …
Beyond shielding: the roles of glycans in the SARS-CoV-2 spike protein
The ongoing COVID-19 pandemic caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) has resulted in more than 28,000,000 infections and 900,000 …
coronavirus 2 (SARS-CoV-2) has resulted in more than 28,000,000 infections and 900,000 …
Structure and inhibition of SARS-CoV-2 spike refolding in membranes
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein binds the
receptor angiotensin converting enzyme 2 (ACE2) and drives virus-host membrane fusion …
receptor angiotensin converting enzyme 2 (ACE2) and drives virus-host membrane fusion …
Coiled coils–a model system for the 21st century
α-Helical coiled coils were described more than 60 years ago as simple, repetitive structures
mediating oligomerization and mechanical stability. Over the past 20 years, however, they …
mediating oligomerization and mechanical stability. Over the past 20 years, however, they …
A Basis Set of de Novo Coiled-Coil Peptide Oligomers for Rational Protein Design and Synthetic Biology
Protein engineering, chemical biology, and synthetic biology would benefit from toolkits of
peptide and protein components that could be exchanged reliably between systems while …
peptide and protein components that could be exchanged reliably between systems while …
Type V secretion: mechanism (s) of autotransport through the bacterial outer membrane
Autotransport in Gram-negative bacteria denotes the ability of surface-localized proteins to
cross the outer membrane (OM) autonomously. Autotransporters perform this task with the …
cross the outer membrane (OM) autonomously. Autotransporters perform this task with the …
Molecular architecture and activation of the insecticidal protein Vip3Aa from Bacillus thuringiensis
Bacillus thuringiensis Vip3 (V egetative I nsecticidal P rotein 3) toxins are widely used in
biotech crops to control Lepidopteran pests. These proteins are produced as inactive …
biotech crops to control Lepidopteran pests. These proteins are produced as inactive …
The structure and topology of α-helical coiled coils
Abstract α-Helical coiled coils constitute one of the most diverse folds yet described. They
range in length over two orders of magnitude; they form rods, segmented ropes, barrels …
range in length over two orders of magnitude; they form rods, segmented ropes, barrels …
The disposition of the LZCC protein residues in wenxiang diagram provides new insights into the protein–protein interaction mechanism
GP Zhou - Journal of Theoretical Biology, 2011 - Elsevier
Wenxiang diagram is a new two-dimensional representation that characterizes the
disposition of hydrophobic and hydrophilic residues in α-helices. In this research, the …
disposition of hydrophobic and hydrophilic residues in α-helices. In this research, the …