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EASL clinical practice guidelines: management of hepatocellular carcinoma
Liver cancer is the fifth most common cancer and the second most frequent cause of cancer-
related death globally. Hepatocellular carcinoma represents about 90% of primary liver …
related death globally. Hepatocellular carcinoma represents about 90% of primary liver …
[HTML][HTML] Mechanistic insight and clinical implications of ischemia/reperfusion injury post liver transplantation
J Liu, K Man - Cellular and molecular gastroenterology and …, 2023 - Elsevier
Ischemia/reperfusion injury is an inevitable process during liver transplantation and can lead
to a high incidence of early allograft dysfunction and graft failure. The mechanism of hepatic …
to a high incidence of early allograft dysfunction and graft failure. The mechanism of hepatic …
[HTML][HTML] Hypothermic oxygenated perfusion in extended criteria donor liver transplantation—A randomized clinical trial
M Ravaioli, G Germinario, G Dajti, M Sessa… - American Journal of …, 2022 - Elsevier
Hypothermic Oxygenated Perfusion (HOPE) of the liver can reduce the incidence of early
allograft dysfunction (EAD) and failure in extended criteria donors (ECD) grafts, although …
allograft dysfunction (EAD) and failure in extended criteria donors (ECD) grafts, although …
Novel real-time prediction of liver graft function during hypothermic oxygenated machine perfusion before liver transplantation
Objective: The aim of this study was to determine the predictive value of machine perfusate
analysis on graft outcome. Background: Ex situ machine perfusion (MP) is gaining …
analysis on graft outcome. Background: Ex situ machine perfusion (MP) is gaining …
Portable hypothermic oxygenated machine perfusion for organ preservation in liver transplantation: A randomized, open-label, clinical trial
Conclusions: HMP-O 2 demonstrates safety and noninferior efficacy for liver graft
preservation in comparison to SCS. Early allograft failure by L-GrAFT 7 was lower in HMP-O …
preservation in comparison to SCS. Early allograft failure by L-GrAFT 7 was lower in HMP-O …
[HTML][HTML] Outcome of liver transplantation with grafts from brain-dead donors treated with dual hypothermic oxygenated machine perfusion, with particular reference to …
Prompted by the utilization of extended criteria donors, dual hypothermic oxygenated
machine perfusion (D-HOPE) was introduced in liver transplantation to improve …
machine perfusion (D-HOPE) was introduced in liver transplantation to improve …
Development and validation of a comprehensive model to estimate early allograft failure among patients requiring early liver retransplant
Importance Expansion of donor acceptance criteria for liver transplant increased the risk for
early allograft failure (EAF), and although EAF prediction is pivotal to optimize transplant …
early allograft failure (EAF), and although EAF prediction is pivotal to optimize transplant …
Danger signals in liver injury and restoration of homeostasis
Damage-associated molecular patterns are signalling molecules involved in inflammatory
responses and restoration of homeostasis. Chronic release of these molecules can also …
responses and restoration of homeostasis. Chronic release of these molecules can also …
Hypothermic oxygenated new machine perfusion system in liver and kidney transplantation of extended criteria donors: first Italian clinical trial
With the aim to explore innovative tools for organ preservation, especially in marginal
organs, we hereby describe a clinical trial of ex-vivo hypothermic oxygenated perfusion …
organs, we hereby describe a clinical trial of ex-vivo hypothermic oxygenated perfusion …
[PDF][PDF] The role of ischemia/reperfusion injury in early hepatic allograft dysfunction
Liver transplantation (LT) is the only available curative treatment for patients with end‐stage
liver disease. Early allograft dysfunction (EAD) is a life‐threatening complication of LT and is …
liver disease. Early allograft dysfunction (EAD) is a life‐threatening complication of LT and is …