Current options for cell therapy in spinal cord injury

I Vismara, S Papa, F Rossi, G Forloni… - Trends in molecular …, 2017 - cell.com
Spinal cord injury (SCI) is a complex pathology that evolves after primary acute mechanical
injury, causing further damage to the spinal cord tissue that exacerbates clinical outcomes …

Crosstalk between stem cell and spinal cord injury: pathophysiology and treatment strategies

A Shao, S Tu, J Lu, J Zhang - Stem cell research & therapy, 2019 - Springer
The injured spinal cord is difficult to repair and regenerate. Traditional treatments are not
effective. Stem cells are a type of cells that have the potential to differentiate into various …

Fat graft enrichment strategies: a systematic review

KS Vyas, HC Vasconez, S Morrison… - Plastic and …, 2020 - journals.lww.com
Background: Autologous fat grafting is a dynamic modality used in plastic surgery as an
adjunct to improve functional and aesthetic form. However, current practices in fat grafting for …

Wnt-modified materials mediate asymmetric stem cell division to direct human osteogenic tissue formation for bone repair

Y Okuchi, J Reeves, SS Ng, DH Doro, S Junyent… - Nature materials, 2021 - nature.com
The maintenance of human skeletal stem cells (hSSCs) and their progeny in bone defects is
a major challenge. Here, we report on a transplantable bandage containing a three …

Ferumoxytol can be used for quantitative magnetic particle imaging of transplanted stem cells

H Nejadnik, P Pandit, O Lenkov, AP Lahiji… - Molecular Imaging and …, 2019 - Springer
Purpose To evaluate, if clinically translatable ferumoxytol nanoparticles can be used for in
vivo detection and quantification of stem cell transplants with magnetic particle imaging …

Nonviral locally injected magnetic vectors for in vivo gene delivery: A review of studies on magnetofection

AA Sizikov, MV Kharlamova, MP Nikitin, PI Nikitin… - Nanomaterials, 2021 - mdpi.com
Magnetic nanoparticles have been widely used in nanobiomedicine for diagnostics and the
treatment of diseases, and as carriers for various drugs. The unique magnetic properties of …

Magnetic resonance imaging of stem cell apoptosis in arthritic joints with a caspase activatable contrast agent

H Nejadnik, D Ye, OD Lenkov, JS Donig, JE Martin… - ACS …, 2015 - ACS Publications
About 43 million individuals in the US encounter cartilage injuries due to trauma or
osteoarthritis, leading to joint pain and functional disability. Matrix-associated stem cell …

Regenerative medicine for spinal cord injury: focus on stem cells and biomaterials

S Papa, F Pizzetti, G Perale… - Expert opinion on …, 2020 - Taylor & Francis
Introduction Spinal cord injury (SCI) is a dramatic medical pathology consequence of a
trauma (primary injury). However, most of the post-traumatic degeneration of the tissue is …

Minicircle microporation-based non-viral gene delivery improved the targeting of mesenchymal stem cells to an injury site

JY Mun, KK Shin, O Kwon, YT Lim, DB Oh - Biomaterials, 2016 - Elsevier
Genetic engineering approaches to improve the therapeutic potential of mesenchymal stem
cells (MSCs) have been made by viral and non-viral gene delivery methods. Viral methods …

A multi-modality imaging strategy to determine the multiple in vivo fates of human umbilical cord mesenchymal stem cells at different periods of acute liver injury …

N Wei, X Chen, D Liu, X Bu, G Wang, X Sun… - Journal of Materials …, 2024 - pubs.rsc.org
Human umbilical cord mesenchymal stem cells (HUCMSCs) are applied for disease therapy
as a new type of drug in many countries. Their effects are not only presented by live cells …