Osteoarthritis is a highly prevalent disease particularly in subjects over 65 years of age
worldwide. While in the past it was considered a mere consequence of cartilage degradation …

Purpose To use meta-analysis techniques to evaluate the efficacy and safety of platelet-rich
plasma (PRP) injections for the treatment knee of osteoarthritis (OA). Methods We performed …

Introduction Platelet-rich plasma (PRP) is nowadays widely applied in different clinical
scenarios, such as orthopedics, ophthalmology and healing therapies, as a growth factor …

Background: Leukocyte-poor platelet-rich plasma (LP-PRP) is hypothesized to be more
suitable for intra-articular injection than leukocyte-rich PRP (LR-PRP) in the treatment of …

Osteoarthritis (OA) is a common disease involving joint damage, an inadequate healing
response and progressive deterioration of the joint architecture. Autologous blood-derived …

Cartilage defects (CDs) and the most common joint disease, osteoarthritis (OA), are
characterized by degeneration of the articular cartilage that ultimately leads to joint …

Objectives Autophagy constitutes a defense mechanism to overcome aging and apoptosis in
osteoarthritic cartilage. Several cytokines and transcription factors are linked to autophagy …

Platelet-rich plasma (PRP) is an autologous concentrated cocktail of growth factors and
inflammatory mediators, and has been considered to be potentially effective for cartilage …

Background: Platelet-rich plasma (PRP) has recently been postulated as a treatment for
osteoarthritis (OA). Although anabolic effects of PRP on chondrocytes are well documented …

Cartilage, especially articular cartilage, is a unique connective tissue consisting of
chondrocytes and cartilage matrix that covers the surface of joints. It plays a critical role in …