Inhalation therapy has been reported as the most effective treatment for respiratory bacterial
infections due to the increasing relevance of drug bioavailability. Drug delivery systems …

In situ forming hydrogels are promising for biomedical applications, especially in drug
delivery. The precursor solution can be injected at the target site, where it undergoes a sol …

During the process of cancer metastasis, various enzymes, cytokines, and factors were
involved, and upregulated cyclooxygenase-2 (COX-2) in tumor cells led to proliferation and …

Oxidation of polysaccharides has been a useful approach to new materials. However,
selectivity in oxidation of polysaccharide macromolecular polyols remains a significant …

Chemical modification of cellulose is challenging due to its low reactivity and poor solubility.
Halogenation followed by displacement reactions has been demonstrated to be a valuable …

A pharmaceutical formulation with favorable pharmacokinetic parameters is more likely to be
efficacious and safe to overcome the failures of the drug resulting from lack of efficacy, poor …

Smart polymeric systems are required that are able to release a therapeutic drug with control
over timing and location of delivery. Herein we have investigated the architecture-controlled …

The present study reveals the syntheses of hydroxypropylcellulose‑(HPC) and
hydroxyethylcellulose‑(HEC) based macromolecular prodrugs (MPDs) of ciprofloxacin (CIP) …

Biodegradable natural and synthetic polymers are widely used in medicine. They are
essential components of drug carriers, scaffolds for tissue engineering and many different …

Present study deals with fabrication of macromolecular prodrugs (MPDs) of flurbiprofen
(FLB) with hydroxyethylcellulose (HEC). FLB was activated using p-toluenesulfonyl chloride …