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Use of human umbilical vein endothelial cells (HUVEC) as a model to study cardiovascular disease: A review
Cardiovascular disease (CVD) is the leading cause of death worldwide, and extensive
research has been performed to understand this disease better, using various experimental …
research has been performed to understand this disease better, using various experimental …
Fibroblast growth factor/fibroblast growth factor receptor system in angiogenesis
Fibroblast growth factors (FGFs) are a family of heparin-binding growth factors. FGFs exert
their pro-angiogenic activity by interacting with various endothelial cell surface receptors …
their pro-angiogenic activity by interacting with various endothelial cell surface receptors …
Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma
Human cancers are complex ecosystems composed of cells with distinct phenotypes,
genotypes, and epigenetic states, but current models do not adequately reflect tumor …
genotypes, and epigenetic states, but current models do not adequately reflect tumor …
[HTML][HTML] Distinct sources of hematopoietic progenitors emerge before HSCs and provide functional blood cells in the mammalian embryo
KE McGrath, JM Frame, KH Fegan, JR Bowen… - Cell reports, 2015 - cell.com
Hematopoietic potential arises in mammalian embryos before adult-repopulating
hematopoietic stem cells (HSCs). At embryonic day 9.5 (E9. 5), we show the first murine …
hematopoietic stem cells (HSCs). At embryonic day 9.5 (E9. 5), we show the first murine …
Tumour vascular targeting
It is now accepted that the growth of solid tumours is dependent on their capacity to acquire
a blood supply, and much effort has been directed towards the development of agents …
a blood supply, and much effort has been directed towards the development of agents …
[HTML][HTML] Endothelial gene expression in kidney transplants with alloantibody indicates antibody-mediated damage despite lack of C4d staining
Anti-HLA alloantibody is a risk factor for graft loss, but does not indicate which kidneys are
experiencing antibody-mediated rejection (ABMR). C4d staining in biopsies is specific for …
experiencing antibody-mediated rejection (ABMR). C4d staining in biopsies is specific for …
Tumor necrosis is an important hallmark of aggressive endometrial cancer and associates with hypoxia, angiogenesis and inflammation responses
G Bredholt, M Mannelqvist, IM Stefansson… - …, 2015 - pmc.ncbi.nlm.nih.gov
Aims Tumor necrosis is associated with aggressive features of endometrial cancer and poor
prognosis. Here, we investigated gene expression patterns and potential treatment targets …
prognosis. Here, we investigated gene expression patterns and potential treatment targets …
Novel role for the potent endogenous inotrope apelin in human cardiac dysfunction
Background—Apelin is among the most potent stimulators of cardiac contractility known.
However, no physiological or pathological role for apelin–angiotensin receptor-like 1 (APJ) …
However, no physiological or pathological role for apelin–angiotensin receptor-like 1 (APJ) …
The influence of biomaterials on endothelial cell thrombogenicity
Driven by tissue engineering and regenerative medicine, endothelial cells are being used in
combination with biomaterials in a number of applications for the purpose of improving …
combination with biomaterials in a number of applications for the purpose of improving …
Endocan expression and relationship with survival in human non–small cell lung cancer
Purpose: We evaluated the expression of endocan, a soluble lung-and kidney-selective
endothelial cell-specific dermatan sulfate proteoglycan, in non–small cell lung tumors …
endothelial cell-specific dermatan sulfate proteoglycan, in non–small cell lung tumors …