How cells move is a fundamental biological question. The directionality of adherent
migrating cells depends on the assembly and disassembly (turnover) of focal adhesions …

The cytoskeleton comprises three polymerizing structures that have been studied for a long
time, actin microfilaments, microtubules and intermediate filaments, plus more recently …

Septins are cytoskeletal proteins conserved from algae and protists to mammals. A unique
feature of septins is their presence as heteromeric complexes that polymerize into filaments …

Cell adhesion and migration depend on the assembly and disassembly of adhesive
structures known as focal adhesions. Cells adhere to the extracellular matrix (ECM) and …

Septins are a family of membrane-associated cytoskeletal guanine-nucleotide binding
proteins that play crucial roles in various cellular processes, such as cell division …

Background Septins are cytoskeletal proteins with filament forming capabilities, which have
multiple roles during cell division, cellular polarization, morphogenesis, and membrane …

The molecular basis for septin filament assembly has begun to emerge over recent years.
These filaments are essential for many septin functions which depend on their association …

The septins of the yeast Saccharomyces cerevisiae assemble into hetero-octameric rods by
alternating interactions between neighboring G-domains or N-and C-termini, respectively …

Cleavage of one cell into two is the most dramatic event in the life of a cell. Plasma
membrane fission occurs within a narrow intercellular bridge (ICB) between the daughter …

Septins are cytoskeletal proteins and their interaction with membranes is crucial for their role
in various cellular processes. Septins have polybasic regions (PB1 and PB2) which are …