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Design, classification, and adverse effects of NSAIDs: A review on recent advancements
Inflammation is a hallmark of many diseases, including cancer, neurodegenerative diseases
like Alzheimer's, type II diabetes, rheumatoid arthritis, and asthma. Nonsteroidal anti …
like Alzheimer's, type II diabetes, rheumatoid arthritis, and asthma. Nonsteroidal anti …
Selective COX-2 inhibitors as anticancer agents: a patent review (2018-2023)
Introduction COX-2 is a crucial enzyme in the manufacture of prostaglandins. The enzyme's
metabolites might have an important function as regulators of the inflammatory response …
metabolites might have an important function as regulators of the inflammatory response …
Optimizing bioreactor conditions for Spirulina fermentation by Lactobacillus helveticus and Kluyveromyces marxianus: Impact on chemical & bioactive properties
This study focused on optimizing the production of fermented Spirulina (FS) products using a
bioactivity-guided strategy with Lactobacillus helveticus B-4526 and Kluyveromyces …
bioactivity-guided strategy with Lactobacillus helveticus B-4526 and Kluyveromyces …
Novel tryptanthrin derivatives with benzenesulfonamide substituents: Design, synthesis, and anti-inflammatory evaluation
J Du, P Liu, Y Zhu, G Wang, S **ng, T Liu, J **a… - European Journal of …, 2023 - Elsevier
Herein, two series of tryptanthrin derivatives with benzenesulfonamide substituents were
designed and synthesized to discover novel anti-inflammatory agents. The anti-inflammatory …
designed and synthesized to discover novel anti-inflammatory agents. The anti-inflammatory …
Novel thiadiazol derivatives; design, synthesis, biological activity, molecular docking and molecular dynamics
Currently, selective COX-2 inhibitors are used as a novel alternative approach in the course
of pain management due to their reduced adverse that generally occur after COX-1 …
of pain management due to their reduced adverse that generally occur after COX-1 …
Discovery of novel deoxyvasicinone derivatives with benzenesulfonamide substituents as multifunctional agents against Alzheimer's disease
S Dong, J **a, F Wang, L Yang, S **ng, J Du… - European Journal of …, 2024 - Elsevier
A series of deoxyvasicinone derivatives with benzenesulfonamide substituents were
designed and synthesized to find a multifunctional anti-Alzheimer's disease (AD) drug. The …
designed and synthesized to find a multifunctional anti-Alzheimer's disease (AD) drug. The …
Novel analytical sensing strategy using a palladium nanomaterial-based electrode for nimesulide electrochemical reduction
Nimesulide (NIM) is a non-steroidal anti-inflammatory drug considered an emerging
contaminant. Thus, a novel sensing platform composed of an ionic silsesquioxane material …
contaminant. Thus, a novel sensing platform composed of an ionic silsesquioxane material …
Novel quinoline-based derivatives: A new class of PDE4B inhibitors for adjuvant-induced arthritis
S **ng, W Fan, J Chen, J Du, T Liu, S Dong… - European Journal of …, 2022 - Elsevier
A total of 31 quinoline-based derivatives were designed and synthesized to develop novel
anti-inflammatory drugs. After the toxicity of synthetic compounds to RAW264. 7 cells were …
anti-inflammatory drugs. After the toxicity of synthetic compounds to RAW264. 7 cells were …
Novel nimesulide multicomponent solid forms: screening, synthesis, thermoanalytical study and characterization
Nimesulide (NMS) is a widely used non-steroidal anti-inflammatory drug, however, presents
low aqueous solubility. One way to overcome the solubility issue of drugs is altering their …
low aqueous solubility. One way to overcome the solubility issue of drugs is altering their …
Synergy between cyclooxygenase-2 inhibitors and hyaluronic acid in the treatment of osteoarthritis: Illumination of signaling cascade, nanotechnology-driven delivery …
Osteoarthritis (OA) is generally caused by a variety of risk factors, the most notable of which
are growing age and obesity. Pathophysiologically, chondrocytes alter their morphology and …
are growing age and obesity. Pathophysiologically, chondrocytes alter their morphology and …