Zika virus
S Masmejan, D Musso, M Vouga, L Pomar… - Pathogens, 2020 - mdpi.com
Zika virus (ZIKV), a neurotropic single-stranded RNA flavivirus, remains an important cause
of congenital infection, fetal microcephaly, and Guillain-Barré syndrome in populations …
of congenital infection, fetal microcephaly, and Guillain-Barré syndrome in populations …
Updates on dengue vaccine and antiviral: where are we heading?
Approximately 100–400 million people from more than 100 countries in the tropical and
subtropical world are affected by dengue infections. Recent scientific breakthroughs have …
subtropical world are affected by dengue infections. Recent scientific breakthroughs have …
Prior Dengue virus exposure shapes T cell immunity to Zika virus in humans
While progress has been made in characterizing humoral immunity to Zika virus (ZIKV) in
humans, little is known regarding the corresponding T cell responses to ZIKV. Here, we …
humans, little is known regarding the corresponding T cell responses to ZIKV. Here, we …
Dengue virus-reactive CD8+ T cells mediate cross-protection against subsequent Zika virus challenge
J Wen, A Elong Ngono, JA Regla-Nava, K Kim… - Nature …, 2017 - nature.com
Zika virus (ZIKV) and dengue virus (DENV) are antigenically related flaviviruses that share
cross-reactivity in antibody and T cell responses, and co-circulate in increasing numbers of …
cross-reactivity in antibody and T cell responses, and co-circulate in increasing numbers of …
Innate and adaptive immune evasion by dengue virus
Dengue is a mosquito-borne disease which causes significant public health concerns in
tropical and subtropical countries. Dengue virus (DENV) has evolved various strategies to …
tropical and subtropical countries. Dengue virus (DENV) has evolved various strategies to …
Immune-mediated pathogenesis in dengue virus infection
Dengue virus (DENV) infection is one of the major public health concerns around the globe,
especially in the tropical regions of the world that contribute to 75% percent of dengue …
especially in the tropical regions of the world that contribute to 75% percent of dengue …
Critical role of CD4+ T cells and IFNγ signaling in antibody-mediated resistance to Zika virus infection
Protective adaptive immunity to Zika virus (ZIKV) has been mainly attributed to cytotoxic
CD8+ T cells and neutralizing antibodies, while the participation of CD4+ T cells in …
CD8+ T cells and neutralizing antibodies, while the participation of CD4+ T cells in …
Zika vaccines and therapeutics: landscape analysis and challenges ahead
A Wilder-Smith, K Vannice, A Durbin, J Hombach… - BMC medicine, 2018 - Springer
Abstract Background Various Zika virus (ZIKV) vaccine candidates are currently in
development. Nevertheless, unique challenges in clinical development and regulatory …
development. Nevertheless, unique challenges in clinical development and regulatory …
Global Assessment of Dengue Virus-Specific CD4+ T Cell Responses in Dengue-Endemic Areas
Background Dengue is a major public health problem worldwide. Assessment of adaptive
immunity is important to understanding immunopathology and to define correlates of …
immunity is important to understanding immunopathology and to define correlates of …
[HTML][HTML] Current understanding of the role of T cells in chikungunya, dengue and zika infections
Arboviral infections such as Chikungunya (CHIKV), Dengue (DENV) and Zika (ZIKV) are a
major disease burden in tropical and sub-tropical countries, and there are no effective …
major disease burden in tropical and sub-tropical countries, and there are no effective …