[HTML][HTML] Recent advances in biological and medicinal profile of schiff bases and their metal complexes: An updated version (2018–2023)
S Thakur, A Jaryal, A Bhalla - Results in Chemistry, 2024 - Elsevier
Schiff bases are most the widely used class of molecules in organic as well as in inorganic
chemistry and are well known for fabricating stable metal complexes. Schiff bases and their …
chemistry and are well known for fabricating stable metal complexes. Schiff bases and their …
Benzimidazole and Benzoxazole Derivatives Against Alzheimer's Disease
Benzimidazole and benzoxazole derivatives are included in the category of medical drugs in
a wide range of areas such as anticancer, anticoagulant, antihypertensive, anti …
a wide range of areas such as anticancer, anticoagulant, antihypertensive, anti …
Fabrication of hybrid coated microneedles with donepezil utilizing digital light processing and semisolid extrusion printing for the management of Alzheimer's disease
PK Monou, EG Andriotis, E Saropoulou… - Molecular …, 2024 - ACS Publications
Microneedle (MN) patches are gaining increasing attention as a cost-effective technology for
delivering drugs directly into the skin. In the present study, two different 3D printing …
delivering drugs directly into the skin. In the present study, two different 3D printing …
Investigation of novel benzimidazole-based indole/thiazole hybrids derivatives as effective anti-diabetics and anti-alzheimer's agents: Structure-activity relationship …
Alzheimer's disease (AD) and type 2 diabetes mellitus (T2DM) are common in developed
countries and their incidence is increasing. The research is mostly concentrated on the …
countries and their incidence is increasing. The research is mostly concentrated on the …
Acetylcholine and butyrylcholine esterase inhibitory potential of newly synthesized halogenated compounds: In vitro, in silico and MD simulation
Schiff bases have numerous applications especially in the medicinal chemistry. Kee** in
view their importance, two new compounds;(E)-2-(((4‑bromo-2-(trifluoromethyl) phenyl) …
view their importance, two new compounds;(E)-2-(((4‑bromo-2-(trifluoromethyl) phenyl) …
Design, Synthesis, In Vitro Biological Evaluation and In Silico Molecular Docking Study of Benzimidazole-Based Oxazole Analogues: A Promising …
Alzheimer's disease (AD) is a degenerative neurological condition that severely affects the
elderly and is clinically recognised by a decrease in cognition and memory. The treatment of …
elderly and is clinically recognised by a decrease in cognition and memory. The treatment of …
Design, synthesis, in vitro acetylcholinesterase, butyrylcholinesterase activities, and in silico molecular docking study of oxindole-oxadiazole hybrid analogues
Alzheimer's disease is a neurological disorder characterized by cognitive dysfunction and
deficits in activities of daily living. There is no drug available for Alzheimer's at the moment …
deficits in activities of daily living. There is no drug available for Alzheimer's at the moment …
In-vitro and in-silico assessment of thiazole-thiazolidinone derivatives as selective inhibitors of urease and α-glucosidase
Aims Current research work aims to synthesize hybrid compounds with a thiazole-
thiazolidinone structure, as potent inhibitors of urease and α-glucosidase enzymes …
thiazolidinone structure, as potent inhibitors of urease and α-glucosidase enzymes …
[HTML][HTML] Design, synthesis, in vitro biological assessment and in silico molecular modeling study of thiazole-thiazolidinone derivatives as potent anti-cancer agents
The current study addressed the synthesis of thiazole-based thiazolidinone derivatives (1–
18) using stepwise reaction processes, and their structure was confirmed using various …
18) using stepwise reaction processes, and their structure was confirmed using various …
In vitro and in silico correlation of bis-thiazole based Schiff base hybrids analogues: A computational approach develop to promising acetylcholinesterase and …
We have synthesized sixteen bis-thiazole based Schiff bases hybrid derivatives (1–16) and
evaluated against acetylcholinesterase and butyrylcholinesterase enzymes. All analogues …
evaluated against acetylcholinesterase and butyrylcholinesterase enzymes. All analogues …