Specific immune-based diagnosis of tuberculosis
Current diagnostic tests for tuberculosis based on tuberculin have poor specificity, and both
BCG vaccination and exposure to non-tuberculosis mycobacteria produce a response …
BCG vaccination and exposure to non-tuberculosis mycobacteria produce a response …
BCG—different strains, different vaccines?
MA Behr - The Lancet infectious diseases, 2002 - thelancet.com
After nearly a century of use, BCG vaccines continue to generate controversy and confusion.
Their ability to prevent tuberculosis in studies has been inconsistent. When they have been …
Their ability to prevent tuberculosis in studies has been inconsistent. When they have been …
Purification and characterization of a low-molecular-mass T-cell antigen secreted by Mycobacterium tuberculosis
A novel immunogenic antigen, the 6-kDa early secretory antigenic target (ESAT-6), from
short-term culture filtrates of Mycobacterium tuberculosis was purified by hydrophobic …
short-term culture filtrates of Mycobacterium tuberculosis was purified by hydrophobic …
Evidence for occurrence of the ESAT-6 protein in Mycobacterium tuberculosis and virulent Mycobacterium bovis and for its absence in Mycobacterium bovis BCG
M Harboe, T Oettinger, HG Wiker… - Infection and …, 1996 - Am Soc Microbiol
ESAT-6 is a secreted protein present in the short-term culture filtrate of Mycobacterium
tuberculosis after growth on a synthetic Sauton medium. ESAT-6 has recently been …
tuberculosis after growth on a synthetic Sauton medium. ESAT-6 has recently been …
Liquid vs. solid culture for tuberculosis: performance and cost in a resource-constrained setting
VN Chihota, AD Grant, K Fielding… - … of tuberculosis and …, 2010 - ingentaconnect.com
SETTING: National Health Laboratory Services tuberculosis (TB) laboratory, South Africa.
OBJECTIVES: To compare Mycobacterium Growth Indicator Tube (MGIT) with Löwenstein …
OBJECTIVES: To compare Mycobacterium Growth Indicator Tube (MGIT) with Löwenstein …
Proteins released from Mycobacterium tuberculosis during growth
P Andersen, D Askgaard, L Ljungqvist… - Infection and …, 1991 - Am Soc Microbiol
Proteins secreted from Mycobacterium tuberculosis during growth are believed to be
important for protective immunity against tuberculosis. We have investigated the growth of M …
important for protective immunity against tuberculosis. We have investigated the growth of M …
Isolation and partial characterization of major protein antigens in the culture fluid of Mycobacterium tuberculosis
S Nagai, HG Wiker, M Harboe… - Infection and …, 1991 - Am Soc Microbiol
Five actively secreted proteins (MPT32, MPT45, MPT51, MPT53, and MPT63) and the
MPT46 protein were purified to homogeneity from Mycobacterium tuberculosis culture fluid …
MPT46 protein were purified to homogeneity from Mycobacterium tuberculosis culture fluid …
T Cell Response to Mycobacterium tuberculosis
IM Orme, P Andersen, WH Boom - Journal of Infectious …, 1993 - academic.oup.com
The T cell-mediated acquired immune response to infection with Mycobacterium
tuberculosis, both in humans and in experimental models in the mouse, is a complex event …
tuberculosis, both in humans and in experimental models in the mouse, is a complex event …
New tools and emerging technologies for the diagnosis of tuberculosis: part I. Latent tuberculosis
Nearly a third of the world's population is estimated to be infected with Mycobacterium
tuberculosis. This enormous pool of latently infected individuals poses a major hurdle for …
tuberculosis. This enormous pool of latently infected individuals poses a major hurdle for …
New tools and emerging technologies for the diagnosis of tuberculosis: part II. Active tuberculosis and drug resistance
Tuberculosis (TB) is one of the world's most important infectious causes of morbidity and
mortality among adults. Between 8 and 9 million develop TB disease, and approximately 2 …
mortality among adults. Between 8 and 9 million develop TB disease, and approximately 2 …