PAtbP-EnC: Identifying anti-tubercular peptides using multi-feature representation and genetic algorithm-based deep ensemble model

S Akbar, A Raza, T Al Shloul, A Ahmad, A Saeed… - IEEE …, 2023 - ieeexplore.ieee.org
Mycobacterium tuberculosis, a highly perilous pathogen in humans, serves as the causative
agent of tuberculosis (TB), affecting nearly 33% of the global population. With the increasing …

iAFPs-EnC-GA: identifying antifungal peptides using sequential and evolutionary descriptors based multi-information fusion and ensemble learning approach

A Ahmad, S Akbar, M Tahir, M Hayat, F Ali - Chemometrics and Intelligent …, 2022 - Elsevier
Fungal infections have become a serious health concern for human beings worldwide.
Fungal infections usually occur when the invading fungus appear on a particular part of the …

iAtbP-Hyb-EnC: Prediction of antitubercular peptides via heterogeneous feature representation and genetic algorithm based ensemble learning model

S Akbar, A Ahmad, M Hayat, AU Rehman… - Computers in Biology …, 2021 - Elsevier
Tuberculosis (TB) is a worldwide illness caused by the bacteria Mycobacterium tuberculosis.
Owing to the high prevalence of multidrug-resistant tuberculosis, numerous traditional …

A treatise to computational approaches towards prediction of membrane protein and its subtypes

AH Butt, N Rasool, YD Khan - The Journal of membrane biology, 2017 - Springer
Membrane proteins are vital mediating molecules responsible for the interaction of a cell
with its surroundings. These proteins are involved in different functionalities such as ferrying …

Identification of membrane protein types via multivariate information fusion with Hilbert–Schmidt independence criterion

H Wang, Y Ding, J Tang, F Guo - Neurocomputing, 2020 - Elsevier
Membrane proteins perform a variety of functions vital to the survival of organisms, such as
oxidoreductase, transferase or hydrolase. If the type of membrane protein can be detected …

Prediction of antiviral peptides using transform evolutionary & SHAP analysis based descriptors by incorporation with ensemble learning strategy

S Akbar, F Ali, M Hayat, A Ahmad, S Khan… - … and Intelligent Laboratory …, 2022 - Elsevier
Viral diseases are a major health concern in the last few years. Antiviral peptides (AVPs)
belong to a type of antimicrobial peptides (AMPs) that have the high potential to defend the …

iMethyl-STTNC: Identification of N6-methyladenosine sites by extending the idea of SAAC into Chou's PseAAC to formulate RNA sequences

S Akbar, M Hayat - Journal of theoretical biology, 2018 - Elsevier
Abstract N 6-methyladenosine (m 6 A) is a vital post-transcriptional modification, which adds
another layer of epigenetic regulation at RNA level. It chemically modifies mRNA that effects …

Predicting membrane protein types using various decision tree classifiers based on various modes of general PseAAC for imbalanced datasets

ES Sankari, D Manimegalai - Journal of theoretical biology, 2017 - Elsevier
Predicting membrane protein types is an important and challenging research area in
bioinformatics and proteomics. Traditional biophysical methods are used to classify …

iACP-GAEnsC: Evolutionary genetic algorithm based ensemble classification of anticancer peptides by utilizing hybrid feature space

S Akbar, M Hayat, M Iqbal, MA Jan - Artificial intelligence in medicine, 2017 - Elsevier
Cancer is a fatal disease, responsible for one-quarter of all deaths in developed countries.
Traditional anticancer therapies such as, chemotherapy and radiation, are highly expensive …

iMem-2LSAAC: a two-level model for discrimination of membrane proteins and their types by extending the notion of SAAC into Chou's pseudo amino acid …

M Arif, M Hayat, Z Jan - Journal of Theoretical Biology, 2018 - Elsevier
Membrane proteins execute significant roles in cellular processes of living organisms,
ranging from cell signaling to cell adhesion. As a major part of a cell, the identification of …