Despite the increasing use and success of interventional coronary reperfusion strategies,
morbidity and mortality from acute myocardial infarction are still substantial. Myocardial …

Acute myocardial infarction (AMI) and the heart failure (HF) that often follows are among the
leading causes of death and disability worldwide. As such, new treatments are needed to …

As reperfusion therapies have become more widely used in acute myocardial infarction
patients, ischemia-induced myocardial damage has been markedly reduced, but reperfusion …

After a reperfused myocardial infarction (MI), dynamic tissue changes occur (edema,
inflammation, microvascular obstruction, hemorrhage, cardiomyocyte necrosis, and …

Background Reperfusion may cause injuries to the myocardium in ischemia situation.
Emerging studies suggest that exosomes may serve as key mediators in myocardial …

Harnessing the potential beneficial effects of kinase signalling through the generation of
direct kinase activators remains an underexplored area of drug development,,,–. This also …

The roles and the underlying mechanisms of M1-type macrophages in angiogenesis and
postmyocardial infarction (MI) cardiac repair have remained unclear. In this study, we …

Acute myocardial infarction (AMI) and the heart failure (HF) which may follow are among the
leading causes of death and disability worldwide. As such, new therapeutic interventions are …

The coronary circulation is both culprit and victim of acute myocardial infarction. The rupture
of an epicardial atherosclerotic plaque with superimposed thrombosis causes coronary …

Thrombolytic therapy and revascularization strategies create a complete recanalization of
the occluded epicardial coronary artery in patients with myocardial infarction (MI). However …