Dimethyl fumarate (DMF) is a fumaric acid derivative clinically approved for the treatment of
some inflammatory diseases, but the underlying mechanism for its therapeutic effects …

Developments in basic stem cell biology have paved the way for technology translation in
human medicine. An exciting prospective use of stem cells is the ex vivo generation of …

Hepatocyte‐like cells (HLCs) derived from pluripotent stem cells (PSCs) or direct
reprogramming are an unlimited source of human hepatocytes for biomedical applications …

This study aimed to clarify the nephroprotective effect of dimethyl fumarate (DMF) against Di
(2-ethylhexyl) phthalate (DEHP)-induced nephrotoxicity in both in vitro and in vivo models …

Dimethyl fumarate (DMF) is pharmaceutical activator of the transcription factor nuclear factor
erythroid 2-related factor 2 (Nrf2), which regulates of many cellular antioxidant response …

To accurately study human organ function and disease 'in the dish', it is necessary to
develop reliable cell-based models that closely track human physiology. Our interest lay with …

Aquaculture needs effective antibiotic alternatives to control outbreaks of intestinal
inflammation, as well as liver inflammation and metabolic disorder caused by enteritis …

Introduction Despite improvements in clinical management of hepatocellular carcinoma
(HCC), prognosis remains poor with a 5-year survival rate less than 40%. Drug resistance in …

The large-scale production and frequent use of endocrine-disrupting chemicals (EDCs)
have led to the continuous release and wide distribution of these pollutions in the natural …

Regenerative medicine aims to replace damaged tissues by stimulating endogenous tissue
repair or by transplanting autologous or allogeneic cells. Due to their capacity to produce …