EDC-2: the Endocrine Society's second scientific statement on endocrine-disrupting chemicals
Abstract The Endocrine Society's first Scientific Statement in 2009 provided a wake-up call to
the scientific community about how environmental endocrine-disrupting chemicals (EDCs) …
the scientific community about how environmental endocrine-disrupting chemicals (EDCs) …
Exposure to endocrine disruptors during adulthood: consequences for female fertility
S Rattan, C Zhou, C Chiang… - Journal of …, 2017 - joe.bioscientifica.com
Endocrine disrupting chemicals are ubiquitous chemicals that exhibit endocrine disrupting
properties in both humans and animals. Female reproduction is an important process, which …
properties in both humans and animals. Female reproduction is an important process, which …
Roles of reactive oxygen species and antioxidants in ovarian toxicity
PJ Devine, SD Perreault, U Luderer - Biology of reproduction, 2012 - academic.oup.com
Proper functioning of the ovary is critical to maintain fertility and overall health, and ovarian
function depends on the maintenance and normal development of ovarian follicles. This …
function depends on the maintenance and normal development of ovarian follicles. This …
Effects of endocrine-disrupting chemicals on the ovary
S Patel, C Zhou, S Rattan, JA Flaws - Biology of reproduction, 2015 - academic.oup.com
Endocrine-disrupting chemicals (EDCs) are found abundantly in the environment, resulting
in daily human exposure. This is of concern because many EDCs are known to target the …
in daily human exposure. This is of concern because many EDCs are known to target the …
Bisphenol A impairs follicle growth, inhibits steroidogenesis, and downregulates rate-limiting enzymes in the estradiol biosynthesis pathway
J Peretz, RK Gupta, J Singh… - Toxicological …, 2011 - academic.oup.com
Bisphenol A (BPA) is used as the backbone for plastics and epoxy resins, including various
food and beverage containers. BPA has also been detected in 95% of random urine …
food and beverage containers. BPA has also been detected in 95% of random urine …
Di (2-ethylhexyl) phthalate inhibits antral follicle growth, induces atresia, and inhibits steroid hormone production in cultured mouse antral follicles
Abstract Di (2-ethylhexyl) phthalate (DEHP) is a ubiquitous environmental toxicant found in
consumer products that causes ovarian toxicity. Antral follicles are the functional ovarian …
consumer products that causes ovarian toxicity. Antral follicles are the functional ovarian …
Fetal and neonatal exposure to the endocrine disruptor methoxychlor causes epigenetic alterations in adult ovarian genes
Exposure to endocrine-disrupting chemicals during development could alter the epigenetic
programming of the genome and result in adult-onset disease. Methoxychlor (MXC) and its …
programming of the genome and result in adult-onset disease. Methoxychlor (MXC) and its …
Di-(2-ethylhexyl) phthalate and mono-(2-ethylhexyl) phthalate inhibit growth and reduce estradiol levels of antral follicles in vitro
RK Gupta, JM Singh, TC Leslie, S Meachum… - Toxicology and applied …, 2010 - Elsevier
Any insult that affects survival of ovarian antral follicles can cause abnormal estradiol
production and fertility problems. Phthalate esters (PEs) are plasticizers used in a wide …
production and fertility problems. Phthalate esters (PEs) are plasticizers used in a wide …
Mono (2-ethylhexyl) phthalate accelerates early folliculogenesis and inhibits steroidogenesis in cultured mouse whole ovaries and antral follicles
PR Hannon, KE Brannick, W Wang… - Biology of …, 2015 - academic.oup.com
Humans are ubiquitously exposed to di (2-ethylhexyl) phthalate (DEHP), which is an
environmental toxicant present in common consumer products. DEHP potentially targets the …
environmental toxicant present in common consumer products. DEHP potentially targets the …
Developmental methoxychlor exposure affects multiple reproductive parameters and ovarian folliculogenesis and gene expression in adult rats
AME Armenti, AM Zama, L Passantino… - Toxicology and applied …, 2008 - Elsevier
Methoxychlor (MXC) is an organochlorine pesticide with estrogenic, anti-estrogenic, and anti-
androgenic properties. To investigate whether transient developmental exposure to MXC …
androgenic properties. To investigate whether transient developmental exposure to MXC …