Recent advances in the use of mesoporous silica nanoparticles for the diagnosis of bacterial infections

D Şen Karaman, A Pamukçu… - International Journal …, 2021 - Taylor & Francis
Public awareness of infectious diseases has increased in recent months, not only due to the
current COVID-19 outbreak but also because of antimicrobial resistance (AMR) being …

Multimodality imaging of silica and silicon materials in vivo

DŞ Karaman, MP Sarparanta… - Advanced …, 2018 - Wiley Online Library
Recent progress in the development of silica‐and silicon‐based multimodality imaging
nanoprobes has advanced their use in image‐guided drug delivery, and the development of …

Ratiometric sensing and imaging of intracellular pH using polyethylenimine-coated photon upconversion nanoprobes

T Nareoja, T Deguchi, S Christ, R Peltomaa… - Analytical …, 2017 - ACS Publications
Measurement of changes of pH at various intracellular compartments has potential to solve
questions concerning the processing of endocytosed material, regulation of the acidification …

Feasibility study of the permeability and uptake of mesoporous silica nanoparticles across the blood-brain barrier

H Baghirov, D Karaman, T Viitala, A Duchanoy… - PLoS …, 2016 - journals.plos.org
Drug delivery into the brain is impeded by the blood-brain-barrier (BBB) that filters out the
vast majority of drugs after systemic administration. In this work, we assessed the transport …

Preventing Plasmon Coupling between Gold Nanorods Improves the Sensitivity of Photoacoustic Detection of Labeled Stem Cells in Vivo

J Comenge, O Fragueiro, J Sharkey, A Taylor, M Held… - ACS …, 2016 - ACS Publications
Gold nanorods are excellent contrast agents for imaging technologies which rely on near-
infrared absorption such as photoacoustic imaging. For cell tracking applications, the cells of …

Sugar-decorated mesoporous silica nanoparticles as delivery vehicles for the poorly soluble drug celastrol enables targeted induction of apoptosis in cancer cells

E Niemelä, D Desai, Y Nkizinkiko, JE Eriksson… - European Journal of …, 2015 - Elsevier
Cancerous cells have a rapid metabolism by which they take up sugars, such as glucose, at
significantly higher rates than normal cells. Celastrol is a traditional herbal medicine known …

Inkjet printing of drug-loaded mesoporous silica nanoparticles—A platform for drug development

H Wickström, E Hilgert, JO Nyman, D Desai… - Molecules, 2017 - mdpi.com
Mesoporous silica nanoparticles (MSNs) have shown great potential in improving drug
delivery of poorly water soluble (BCS class II, IV) and poorly permeable (BCS class III, IV) …

Comparison of polydopamine-coated mesoporous silica nanorods and spheres for the delivery of hydrophilic and hydrophobic anticancer drugs

AK Pada, D Desai, K Sun… - International journal of …, 2019 - mdpi.com
Mesoporous silica nanoparticles (MSNs) have been widely studied as drug delivery systems
in nanomedicine. Surface coating of MSNs have enabled them to perform efficiently in terms …

Analyses in zebrafish embryos reveal that nanotoxicity profiles are dependent on surface-functionalization controlled penetrance of biological membranes

I Paatero, E Casals, R Niemi, E Özliseli… - Scientific reports, 2017 - nature.com
Mesoporous silica nanoparticles (MSNs) are extensively explored as drug delivery systems,
but in depth understanding of design-toxicity relationships is still scarce. We used zebrafish …

Shape engineering boosts antibacterial activity of chitosan coated mesoporous silica nanoparticle doped with silver: a mechanistic investigation

DŞ Karaman, S Sarwar, D Desai, EM Björk… - Journal of Materials …, 2016 - pubs.rsc.org
In this study, mesoporous silica nanoparticles (MSPs) of different size and shape were
developed, and their surface coatings were utilized to study their differential effects in …