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Bioactive peptides of whey: Obtaining, activity, mechanism of action, and further applications
Bioactive peptides derived from diverse food proteins have been part of diverse
investigations. Whey is a rich source of proteins and components related to biological …
investigations. Whey is a rich source of proteins and components related to biological …
The myristoylated alanine-rich C-kinase substrates (MARCKS): A membrane-anchored mediator of the cell function
The myristoylated alanine-rich C-kinase substrate (MARCKS) and the MARCKS-related
protein (MARCKSL1) are ubiquitous, highly conserved membrane-associated proteins …
protein (MARCKSL1) are ubiquitous, highly conserved membrane-associated proteins …
Quantitative label-free mass spectrometry reveals content and signaling differences between neonatal and adult platelets
CS Thom, P Davenport, H Fazelinia… - Journal of Thrombosis …, 2024 - Elsevier
Background Recent clinical studies have shown that transfusions of adult platelets increase
morbidity and mortality in preterm infants. Neonatal platelets are hyporesponsive to agonist …
morbidity and mortality in preterm infants. Neonatal platelets are hyporesponsive to agonist …
Food-derived antithrombotic peptides: Preparation, identification, and interactions with thrombin
S Cheng, M Tu, H Liu, G Zhao, M Du - Critical reviews in food …, 2019 - Taylor & Francis
Thromboembolism and its sequelae have been the leading causes of morbidity and
mortality throughout the world. Food-derived antithrombotic peptides, as potential …
mortality throughout the world. Food-derived antithrombotic peptides, as potential …
[HTML][HTML] The small‐molecule MERTK inhibitor UNC2025 decreases platelet activation and prevents thrombosis
Essentials• Signaling by Gas6 through Tyro3/Axl/Mer receptors is essential for stable platelet
aggregation.• UNC2025 is a small molecule inhibitor of the Mer tyrosine kinase.• UNC2025 …
aggregation.• UNC2025 is a small molecule inhibitor of the Mer tyrosine kinase.• UNC2025 …
Pathophysiological roles of myristoylated alanine-rich C-kinase substrate (MARCKS) in hematological malignancies
DN Iyer, O Faruq, L Zhang, N Rastgoo, A Liu… - Biomarker …, 2021 - Springer
The myristoylated alanine-rich C-kinase substrate (MARCKS) protein has been at the
crossroads of multiple signaling pathways that govern several critical operations in normal …
crossroads of multiple signaling pathways that govern several critical operations in normal …
MARCKS and lung disease
MARCKS (myristoylated alanine-rich C kinase substrate) is a prominent PKC substrate
expressed in all eukaryotic cells. It is known to bind to and cross-link actin filaments, to serve …
expressed in all eukaryotic cells. It is known to bind to and cross-link actin filaments, to serve …
Recapitulating the potential contribution of protein S-palmitoylation in cancer
S Chaturvedi, A Sonawane - Cancer and Metastasis Reviews, 2025 - Springer
Protein S-palmitoylation is a reversible form of protein lipidation in which the formation of a
thioester bond occurs between a cysteine (Cys) residue of a protein and a 16-carbon fatty …
thioester bond occurs between a cysteine (Cys) residue of a protein and a 16-carbon fatty …
A cell-penetrating MARCKS mimetic selectively triggers cytolytic death in glioblastoma
Glioblastoma (GBM) is an aggressive malignancy with limited effectiveness of standard of
care therapies including surgery, radiation, and temozolomide chemotherapy necessitating …
care therapies including surgery, radiation, and temozolomide chemotherapy necessitating …
The carboxy terminus of yeast Atg13 binds phospholipid membrane via motifs that overlap with the Vac8-interacting domain
Macroautophagy/autophagy is a conserved catabolic recycling pathway involving the
sequestration of cytoplasmic components within double-membrane vesicles termed …
sequestration of cytoplasmic components within double-membrane vesicles termed …