Intracerebral hemorrhage (ICH) is a devastating form of stroke with high morbidity and
mortality. This review article focuses on the epidemiology, cause, mechanisms of injury …

Intracerebral hemorrhage (ICH) accounts for about 10% of all strokes in the United States of
America causing a high degree of disability and mortality. There is initial (primary) brain …

Ferroptosis, a non-apoptotic form of programmed cell death, is triggered by oxidative stress
in cancer, heat stress in plants, and hemorrhagic stroke. A homeostatic transcriptional …

Introduction: Spontaneous non-traumatic intracerebral hemorrhage (ICH) is most often
caused by small vessel diseases: deep perforator arteriopathy (hypertensive arteriopathy) or …

Background and Purpose—Intracerebral hemorrhage leads to disability or death with few
established treatments. Adverse outcomes after intracerebral hemorrhage result from …

Advancements in molecular biology have led to a greater understanding of the individual
proteins responsible for generating cerebral edema. In large part, the study of cerebral …

Background Ferroptosis, as a new form of cell death, is different from other cell deaths such
as autophagy or senescence. Ferroptosis involves in the pathophysiological progress of …

Background Iron from haemolysed blood is implicated in secondary injury after intracerebral
haemorrhage. We aimed to assess the safety of the iron chelator deferoxamine mesylate in …

Hemorrhagic stroke comprises about 20% of all strokes, with intracerebral hemorrhage
(ICH) being the most common type. Frequency of ICH is increased where hypertension is …

Intracerebral haemorrhage accounts for about 10–15% of all strokes and is associated with
high mortality and morbidity. No successful phase 3 clinical trials for this disorder have been …