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Protein engineering of Bacillus acidopullulyticus pullulanase for enhanced thermostability using in silico data driven rational design methods
A Chen, Y Li, J Nie, B McNeil, L Jeffrey, Y Yang… - Enzyme and microbial …, 2015 - Elsevier
Thermostability has been considered as a requirement in the starch processing industry to
maintain high catalytic activity of pullulanase under high temperatures. Four data driven …
maintain high catalytic activity of pullulanase under high temperatures. Four data driven …
Improving alkaline stability of α-L-rhamnosidase from Aspergillus Niger through computational strategy combines with folding free energy and binding free energy
L Li, C Peng, J Gong, X Liu, W Li, Y Zhu, H Ni… - Biochemical Engineering …, 2023 - Elsevier
It is difficult to improve pH stability of enzymes. In the present study, a semi-rational strategy
was validated to improve the alkaline stability of an α-L-rhamnosidase. The strategy …
was validated to improve the alkaline stability of an α-L-rhamnosidase. The strategy …
Identification and Structural Analysis of Amino Acid Substitutions that Increase the Stability and Activity of Aspergillus niger Glucose Oxidase
J Marín-Navarro, N Roupain, D Talens-Perales… - PLoS …, 2015 - journals.plos.org
Glucose oxidase is one of the most conspicuous commercial enzymes due to its many
different applications in diverse industries such as food, chemical, energy and textile. Among …
different applications in diverse industries such as food, chemical, energy and textile. Among …
Role of His-His interaction in Ser474-His475-Tyr476 sequence of chondroitinase ABC I in the enzyme activity and stability
Despite clinical importance of chondroitinase ABC I, its application has been limited due to
thermal instability as reported in the literature. There are various approaches to improve …
thermal instability as reported in the literature. There are various approaches to improve …
Establishment of aromatic pairs at the surface of chondroitinase ABC I: the effect on activity and stability
Removal of chondroitin sulfate glycosaminoglycan (GAG) chains with chondroitinase ABC I
(chABC I) in CNS injury models promotes both saxon regeneration and plasticity. It has been …
(chABC I) in CNS injury models promotes both saxon regeneration and plasticity. It has been …
Methylglyoxal and high glucose inhibit VEGFR2 phosphorylation at specific tyrosine residues
F Betting, G Schlunck, HT Agostini… - … für Naturforschung C, 2022 - degruyter.com
Diabetes is characterized by hyperglycemia and a significant risk of vascular complications.
Vascular endothelial growth factor (VEGF) and its main receptor VEGFR2 (KDR), which is …
Vascular endothelial growth factor (VEGF) and its main receptor VEGFR2 (KDR), which is …
Engineering Saccharomyces cerevisiae for the production of 1, 2-propanediol using glycerol as a carbon and energy source
Z Islam - 2017 - opus.constructor.university
Biodiesel production via transesterification generates approx. 10%(w/w) glycerol, which is
considered as a glut and needs to be valorized. The production of 1, 2-propanediol (1, 2 …
considered as a glut and needs to be valorized. The production of 1, 2-propanediol (1, 2 …