Human T-cell leukemia virus type 1 (HTLV-1) is the causative agent of a fatal malignancy
known as adult T-cell leukemia (ATL). One way to address the pathology of the disease lies …

It has been 30 years since a'new'leukaemia termed adult T-cell leukaemia (ATL) was
described in Japan, and more than 25 years since the isolation of the retrovirus, human T …

Human T-lymphotropic virus 1 (HTLV-1) has infected human beings for thousands of years,
but knowledge about the infection and its pathogenesis is only recently emerging. The virus …

It is estimated that viral infections contribute to 15–20% of all human cancers. As obligatory
intracellular parasites, viruses encode proteins that reprogram host cellular signaling …

Human T cell leukemia virus type I (HTLV-I) causes adult T cell leukemia (ATL) in 2–5% of
carriers after a long latent period. An HTLV-I encoded protein, Tax, induces proliferation and …

Human retroviruses are derived from simian ones through cross-species transmission.
These retroviruses are associated with little pathogenicity in their natural hosts, but in …

Bovine leukemia virus (BLV) and human T-cell leukemia virus type 1 (HTLV-1) make up a
unique retrovirus family. Both viruses induce chronic lymphoproliferative diseases with BLV …

Adult T-cell leukemia (ATL) is an aggressive T-cell malignancy caused by human T-cell
leukemia virus type 1 (HTLV-1) that develops through a multistep carcinogenesis process …

Human T-cell leukemia virus type 1 (HTLV-1) is the causal agent of a neoplastic disease of
CD4+ T cells, adult T-cell leukemia (ATL), and inflammatory diseases including HTLV-1 …

The human T-cell leukemia virus type 1 (HTLV-1) was the first retrovirus discovered to be
causative of a human cancer, adult T-cell leukemia. The transforming entity of HTLV-1 has …