Nucleic acids have attracted widespread attention due to the simplicity with which they can
be designed to form discrete structures and programmed to perform specific functions at the …

Synthetic biology is the discipline of engineering application-driven biological functionalities
that were not evolved by nature. Early breakthroughs of cell engineering, which were based …

Synthetic biology aims to develop engineering-driven approaches to the programming of
cellular functions that could yield transformative technologies. Synthetic gene circuits that …

The design of modular protein logic for regulating protein function at the posttranscriptional
level is a challenge for synthetic biology. Here, we describe the design of two-input AND …

Synthetic biology is bringing together engineers and biologists to design and build novel
biomolecular components, networks and pathways, and to use these constructs to rewire …

Bioengineering can address many important needs, from transformative biomedicine to
environmental remediation. In addition to practical applications, the construction of new …

Logic and memory are essential functions of circuits that generate complex, state-dependent
responses. Here we describe a strategy for efficiently assembling synthetic genetic circuits …

Engineered biological systems that integrate multi-input sensing, sophisticated information
processing, and precisely regulated actuation in living cells could be useful in a variety of …

Computation underlies the organization of cells into higher-order structures, for example
during development or the spatial association of bacteria in a biofilm,,. Each cell performs a …

Synthetic biology is a research field that combines the investigative nature of biology with
the constructive nature of engineering. Efforts in synthetic biology have largely focused on …