Glioblastoma (GBM) is the most common primary brain tumor in adults an carries and carries
a terrible prognosis. The current regiment of surgical resection, radiation, and chemotherapy …

Radiomics describes a broad set of computational methods that extract quantitative features
from radiographic images. The resulting features can be used to inform imaging diagnosis …

Radiation therapy is an important modality used in the treatment of patients with brain
metastatic disease and malignant gliomas. Post-treatment surveillance often involves serial …

Magnetic resonance spectroscopy (MRS) is a technique which combines the ability of
nuclear magnetic resonance (NMR) to differentiate molecules with the imaging features of …

Ionizing radiation (IR) triggers programmed cell death in tumor cells through a variety of
highly regulated processes. Radiation-induced tumor cell death has been studied …

The incidence of brain metastases is increasing as cancer therapies improve and patients
live longer, providing new challenges to the multidisciplinary teams that care for these …

Abstract Purpose of Review Cerebral radiation necrosis (CRN) is a major dose-limiting
adverse event of radiotherapy. The incidence rate of RN varies with the radiotherapy …

Hypoxia, a hallmark characteristic of glioblastoma (GBM) induces changes in the
transcriptome and the proteome of tumor cells. We discovered that hypoxic stress produces …

Despite numerous clinical trials and pre-clinical developments, the treatment of glioblastoma
(GB) remains a challenge. The current survival rate of GB averages one year, even with an …

OBJECTIVE. Differentiation of radiation necrosis (RN) from recurrent tumor (RT) in treated
patients with glioblastoma remains a diagnostic challenge. The purpose of this study is to …