A canonical regulatory pathway involving the members of the Bcl-2 and caspase families
has been established to regulate developmental apoptosis in nematodes and flies …

Understanding how gene expression programs are controlled requires identifying regulatory
relationships between transcription factors and target genes. Gene regulatory networks are …

Cadmium (Cd) is a toxic heavy metal that induces irregularity in numerous lipid metabolic
pathways. Saccharomyces cerevisiae, a model to study lipid metabolism, has been used to …

Biodegradability testing methods being used nowadays have many disadvantages; they are
time-consuming, inefficient medium used, and too much sample needed to do the test. This …

Background Budding yeast, S. cerevisiae, has been used extensively as a model organism
for studying cellular processes in evolutionarily distant species, including humans. However …

Cancer is a devastating disease with a profound impact on society. In recent years, yeast
has provided a valuable contribution with respect to uncovering the molecular mechanisms …

Neuronal accumulation of UBB+ 1, a frameshift variant of ubiquitin B, is a hallmark of
Alzheimer's disease (AD). How UBB+ 1 contributes to neuronal dysfunction remains elusive …

The marked heterogeneity in glioblastoma (GBM) may be induced through dynamic
differentiation and dedifferentiation process of glioma cells. The hypothesis that …

Mitochondria are the dominant source of the cellular energy requirements through oxidative
phosphorylation, but they are also central players in apoptosis. Nutrient availability may …

Programmed cell death (PCD) is an essential cellular mechanism that is evolutionary
conserved, mediated through various pathways and acts by integrating different stimuli …